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Development of cost-effective tools for risk management and traceability systems for marine biotoxins in seafood (BIOTOX)

Objective

The proposed multi-disciplinary project will focus on the development, validation, and standardisation ofreference methods (LC-MS) and cost-effective assays for the identification and quantification of lipophilic marinebiotoxins, which have been included in the European legislation, and for which currently no methods exist.Existing knowledge on functional and biochemical assays will be used. Application of the Biacore SPR biosensortechnology will be applied to establish high throughput analyses. The new methods should lead to replacementof the existing animal tests. A validation study of the developed tests and a feasibility study on the production ofCRMs will be carried out according to international validation protocols. Early warning systems, based on geneexpression and passive samplers will be developed. The second part of this project will focus on measurementsto be taken after the outbreak of a harmful algal bloom, including improvement of decontamination techniquesand implementation of traceability systems. A report on the harmonisation of monitoring, control, traceability, andhandling of shellfish in EU member states will be prepared. An expert panel will guide and help to avoid overlapwith work elsewhere. Links with other EU projects (SHELLFISH, SEAFOODplus and BioCop) will be establishedto strengthen research. Contacts with the CEN and the IRMM (Joint Research Centre) will be established toobtain advice on standardisation and CRM production. The following key deliverables will be produced: assaysfor all lipophilic toxins included in European Directives, SPR technology for high throughput analysis; a referencemethod; an early warning system based on gene expression and/or passive sampling; recommendations on thecertification of reference materials; improved decontamination procedures; report on the harmonisation ofmonitoring, control and handling contaminated shellfish; workshop and training; newsletters...

Call for proposal

FP6-2003-FOOD-2-A
See other projects for this call

Coordinator

STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK
Address
Costerweg 50
9101 Wageningen
Netherlands

Participants (11)

MARINE INSTITUTE
Ireland
Address
Galway Tecchnology Park, Parkmore West
Galway
RIKILT INSTITUTE OF FOOD SAFETY
Netherlands
Address
Bornsesteeg 45
230 Wageningen
THE NORWEGIAN SCHOOL OF VETERINARY SCIENCE
Norway
Address
Ullevaalsveien 72
8146 Oslo
NATIONAL VETERINARY INSTITUTE
Norway
Address
Ullevaalsveien 68
PB 8156 Oslo
NATIONAL UNIVERSITY OF IRELAND
Ireland
Address
Belfield
Dublin 4
CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE SCIENZE DEL MARE
Italy
Address
Via Isonzo 32
Roma
FOOD SAFETY AUTHORITY OF IRELAND
Ireland
Address
Abbey Court, Abbey Street
Dublin
SCIENTIFIC INSTITUTE OF PUBLIC HEALTH
Belgium
Address
J. Wytsmanstraat 14
Brussels
OYSTER CREEK SEAFOODS LIMITED
Ireland
Address
Maree, Oranmore
Galway
BIOSENSE LABORATORIES AS
Norway
Address
Thormoehlensgate 55
Bergen
INSTITUT FRANAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER'
France
Address
Rue Jean Jacques Rousseau, 155
Issy - Les - Moulineaux