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Programmable Artificial Cell Evolution (PACE)

Objective

The integrated project PACE will explore the utilization of the simplest technically feasible elementary living units (artificial cells much simpler than current cells) to build evolvable complex information systems. We will create, analyse and investigate the applications of such systems that process information by self-organization starting at molecular scales. We will also determine whether life-like properties are necessary for computational systems to be fully robust and adaptive and investigate the tension between evolvable living autonomy and programmable utilization.

We will explore the collective properties of artificial cells and demonstrate that they are the right material for building nanoscale robot ecologies. The particular molecular systems we will consider will have genetically controlled catalytic reactions, self-assembly of complex supra-molecular structures, and energy transduction. We will investigate the stepwise evolution of such complex systems by machine complementation and combinatorial search using a programmable microfluidic interface.

We will provide theoretical and simulation frameworks for understanding emergent computational properties of such systems, and experimental frameworks for programming them by evolutionary exploration of chemical reactions. We will integrate and disseminate multidisciplinary European activities to give it a decisive international competitive advantage in this FET.

Funding Scheme

IP - Integrated Project

Coordinator

RUHR-UNIVERSITAET BOCHUM
Address
Universitaetsstrasse 150
44780 Bochum
Germany

Participants (12)

CHALMERS UNIVERSITY OF TECHNOLOGY
Sweden
Address

412 96 Goeteborg
COMUNE DI VENEZIA
Italy
Address
San Polo 1098, Riva Del Vin
30110 Venice
DUBLIN CITY UNIVERSITY
Ireland
Address

Dublin 9
KOEBENHAVNS UNIVERSITET
Denmark
Address
Noerregade 10
1017 Copenhagen
PROTOLIFE S.R.L.
Italy
Address
Via Rizzardi 3
30100 Venezia
PROTOSTREAM GMBH
Germany
Address
Otto-hahn-strasse 15
44227 Dortmund
REED INSTITUTE DBA REED COLLEGE
United States
Address
3203 Se Woodstock Blvd.
Portland, Oregon 97202
SYDDANSK UNIVERSITET
Denmark
Address
Campusvej 55
5230 Odense M
UNIVERSITA CA' FOSCARI DI VENEZIA
Italy
Address
Dorsoduro 3246
30123 Venezia
UNIVERSITAET ZUERICH
Switzerland
Address
Raemistrasse 71
8006 Zuerich
UNIVERSITAT POMPEU FABRA
Spain
Address
Placa De La Merce 10-12
08002 Barcelona
VILNIAUS UNIVERSITETO TEORINES FIZIKOS IR ASTRONOMIJOS INSTITUTO
Lithuania
Address
A. Gostauto 12,
2600 Vilnius