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The impact of key determinants on the current and future burden of cancer in Europe

Objective

Up to 40% of people ever get cancer in Europe and at middle age 40% of the deaths are due to cancer. Since up to 40% of cancers may also be preventable primary prevention remains essential. Entry-points for preventive interventions were identified based on known risk factors for cancer, partly overlapping with other chronic diseases. Yet, with the exception of hygienic and occupational measures and discouraging smoking, primary prevention was not very successful, especially in lower SES-groups, and avoidable exposure to risk factors demands more attention. This project aims to underpin national and European policies to prevent cancer by providing estimates of the potential impact of interventions on determinants of cancer incidence on the future burden of cancer in Europe. Specifically, we aim to: - Estimate the prevalence and quantitative impact of major lifestyle (smoking, excessive alcohol use, fruit and vegetable consumption, overweight and physical activity) and socio-economic determinants on cancer incidence, concerning cancers of the oral cavity, larynx, lung, oesophagus, stomach, pancreas, colo-rectum, bladder, kidney, breast, endometrium and prostate, comprising 60% of the incidence. - Assess the potential to reduce exposure to these determinants by reviewing evidence of effectiveness of interventions and policies as well as barriers to implementation. - Estimate the future burden of cancer across Europe based on autonomous trends and various scenarios of implementation of effective interventions.This coordination action will generate intensive interaction with national and international researchers and policy-makers, who will provide input to scenario development and reflect on its outcome so that ambitious policies can be rolled out. A special website will be designed allowing for interactive development of scenarios and enabling member states to adapt to their needs and circumstances.

Call for proposal

FP6-2003-SSP-3
See other projects for this call

Funding Scheme

CA - Coordination action

Coordinator

ERASMUS UNIVERSITAIR MEDISCH CENTRUM
Address
Dr Molewaterplein 50
PO Box 1738 Rotterdam
Netherlands

Participants (11)

INTERNATIONAL AGENCY FOR RESEARCH ON CANCER
France
Address
150 Cours Albert Thomas
Lyon
INSTITUT CATALA D'ONCOLOGIA
Spain
Address
Avda. Gran Via S/n Km. 2,7
L'hospitalet De Llobregat
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany
Address
Im Neuenheimer Feld 280
Heidelberg
AZIENDA SANITARIA REGIONALE
Italy
Address
Via Martiri Xxx Aprile, 30
Collegno (Torino)
FINNISH CANCER REGISTRY
Finland
Address
Liisankatu 21 B
Helsinki
UNIVERSITY OF OSLO
Norway
Address
Problemveien 7
1072 Blindern Oslo
INSTITUTE OF CANCER RESEARCH AND CURE
Italy
Address
Via Venezian 1
Milan
OFFICE FOR NATIONAL STATISTICS
United Kingdom
Address
1 Drummond Gate
London
DANISH CANCER SOCIETY
Denmark
Address
Strandboulevarden 49
Copenhagen
NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS
Greece
Address
6 Chr. Lada Street
Athens
MARIA SKLODOWSKA-CURIE MEMORIAL CANCER CENTER AND INSTITUTE OF ONCOLOGY
Poland
Address
Roentgena 5
Warsaw