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A Systems Approach to Tissue Engineering Processes and Products

Project information

Grant agreement ID: 500465

  • Start date

    1 March 2005

  • End date

    31 August 2009

Funded under:

FP6-NMP

  • Overall budget:

    € 22 323 908

  • EU contribution

    € 13 063 154

Coordinated by:

ANIKA THERAPEUTICS SRL

Italy

Objective

Tissue Engineering is an emerging collection of technologies aimed at the regeneration of tissues and organs. Whilst TE potentiality on healthcare has already been demonstated, there has been a marked lack of link between the different components such that TE cannot deliver its promise at present. STEPS addresses this by introducing a systems approach to TE and associated technologies. Our objective is to provide a new infrastructure, based on the hypothesis that the only way to successfully implement TE is to link together all aspects of this multi-disciplinary process by applying the logistics of systems engineering. Specifically, the technological components will include cell sourcing and manipulation, novel biomaterial development, bioreactor design and the integration of TE constructs into the living host. The programme incorporates a determination of the socio-economic issues related to ethics and health economics. This will include an assessment of the public acceptability of these emerging technologies and the ability of private and public health insurance to pay for it without detracting from more traditional medical procedures. The Consortium has designed an objective-driven approach, set to deliver radical innovations in the long term as well as new processes, methodologies and products in the short and medium term.

The potential world market for TE products is estimated at 100 billion and we believe that our approach will transform the TE industrial infrastructure to the point to deliver to this market The Consortium comprises 23 partners from 13 European Countries. It includes 6 industrial organizations (4 SMEs) and 17 academic centres. To develop such a highly innovative systems approach to TE, the contribution of a multidisciplinary Consortium, of a critical mass in manpower, and of a substantial financial commitment, is required. These multidisciplinary skills can be found within this European cooperation.

Coordinator

ANIKA THERAPEUTICS SRL

Address

Via Ponte Della Fabbrica 3/B
Abano Terme (Pd)

Italy

Participants (22)

SOFRADIM PRODUCTION

France

LGC LIMITED

United Kingdom

UNIVERSITY OF LIVERPOOL

United Kingdom

CONSIGLIO NAZIONALE DELLE RICERCHE

Italy

UNIVERSITY OF TWENTE

Netherlands

APPLIKON BIOTECHNOLOGY B.V.

Netherlands

BIOMATECH

France

CELLMATRIX AB

Sweden

UNIVERSITY OF BASEL

Switzerland

UNIVERSITAT POLITÈCNICA DE CATALUNYA

Spain

NATIONAL UNIVERSITY OF IRELAND, GALWAY

Ireland

UNIVERSITÄT ULM

Germany

CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN

Germany

POLITECHNIKA WARSZAWSKA (WARSAW UNIVERSITY OF TECHNOLOGY)

Poland

RIGA STRADINS UNIVERSITY

Latvia

THE UNIVERSITY OF BIRMINGHAM

United Kingdom

KATHOLIEKE UNIVERSITEIT LEUVEN

Belgium

ISTITUTO DI RICERCHE FARMACOLOGICHE "MARIO NEGRI"

Italy

THE UNIVERSITY OF BRISTOL

United Kingdom

MEDICAL UNIVERSITY OF VIENNA

Austria

ISTITUTI ORTOPEDICI RIZZOLI

Italy

GOTEBORGS UNIVERSITET (GOTEBORG UNIVERSITY)

Sweden

Project information

Grant agreement ID: 500465

  • Start date

    1 March 2005

  • End date

    31 August 2009

Funded under:

FP6-NMP

  • Overall budget:

    € 22 323 908

  • EU contribution

    € 13 063 154

Coordinated by:

ANIKA THERAPEUTICS SRL

Italy