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Active biomimetic systems

Active biomimetic systems

Objective

The STREP proposed here deals with biomimetics at the supramolecular or subcellular level which covers the nano- and microregime. In this regime, biological systems exhibit many active processes which are driven by a variety of biomolecular nanomaschines o r motors. The biomimetic systems studied in this STREP contain two types of linear motors, growing filaments and stepping motor proteins. Growing filaments generate pushing forces, stepping motor proteins exert pulling forces. The project has several scien tific objectives: to understand the molecular processes which are responsible for the generation of these forces; to elucidate the cooperative behavior of small and large groups of motor molecules which lead to active surface layers and active filament ass emblies or scaffolds; and to control and optimize the properties of these biomimetic systems. The research performed in this STREP is at the cutting edge of science and has a high potential for long-term innovation. Indeed, there are many possible applicat ions in bioengineering, pharmocology, and medicine such as sorting devices for biomolecules and biocolloids, active drug delivery systems, and force generating components for the development of nanoscale manufacturing.

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Coordinator

MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.

Address

Hofgartenstrasse 8
MÜNchen

Germany

Administrative Contact

Reinhard LIPOWSKY (Professor)

Participants (10)

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BASF AKTIENGESELLSCHAFT

Germany

CENTRE NATIONAL DE LA RECHERCE SCIENTIFIQUE

France

EUROPEAN MOLECULAR BIOLOGY LABORATORY

Germany

INSTITUT CURIE SECTION RECHERCHE

France

INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES

China

LEIBNIZ INSTITUT FUER ALTERSFORSCHUNG - FRITZ LIPMANN INSTITUT E.V.

Germany

NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY

China

POLITECNICO DI MILANO

Italy

STICHTING FOM (FUNDAMENTEEL ONDERZOEK DER MATERIE)

Netherlands

UNIVERSITÄT LEIPZIG

Germany

Project information

Grant agreement ID: 516989

  • Start date

    1 May 2005

  • End date

    31 October 2008

Funded under:

FP6-NMP

  • Overall budget:

    € 2 501 325

  • EU contribution

    € 2 150 000

Coordinated by:

MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.

Germany