Obiettivo Primary targets of FP6 are activities for the combat of multigenic complex diseases such as cancer, diabetes and heart diseases. These diseases, like many others, are caused by disturbances in the complex networks of biological processes in the organisms. Prevention, diagnosis and therapy of these diseases require a detailed understanding of these processes in health and disease, based on the application of techniques from the area of functional genomics on the individual patient, combined with the development of modelling systems, that are able to model the disease process, based on available information as well as the information gained on the individual (genetic factors, chromosomal changes, expression patterns on the RNA and protein levels etc.). In this coordination action (CA) we propose to develop a European infrastructure for such a systems biology approach to combat complex diseases. While we plan to focus on cancer in our initial work, we expect this approach and infrastructure component to become a key instrument in improving diagnosis and therapy of many other complex diseases. This proposal will unite the effort of groups at the forefront of systems biology and modelling, of functional genomics and some of the foremost centres of cancer research. Major goals will be to integrate data and analysis resources available at the participating centres, as well as other centres world wide, to develop and use new mechanisms to identify the pathways likely to be most relevant to the problem domain (cancer), to incorporate these into the models, and to carry out benchmarking studies on the pilot scale to identify strength and weaknesses of current approaches. A major effort will be also invested into a strong outreach component, designed to create local networks contributing to the work of each center, and to educate researchers throughout Europe to the new possibilities and concepts. Campo scientifico natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsmedical and health sciencesclinical medicineendocrinologydiabetesmedical and health sciencesclinical medicineoncologynatural sciencesbiological sciencesgeneticsRNAnatural sciencescomputer and information sciencessoftwaresoftware applicationssimulation software Programma(i) FP6-LIFESCIHEALTH - Life sciences, genomics and biotechnology for health: Thematic Priority 1 under the Focusing and Integrating Community Research programme 2002-2006. Argomento(i) LSH-2004-1.1.0-2 - Topics for CA in the area of Fundamental knowledge and basic tools for functional genomics in all organisms Invito a presentare proposte FP6-2004-LIFESCIHEALTH-5 Vedi altri progetti per questo bando Meccanismo di finanziamento CA - Coordination action Coordinatore MAX PLANCK SOCIETY REPRESENTED BY THE MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS Contributo UE Nessun dato Indirizzo Ihnestr. 73 BERLIN Germania Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Partecipanti (7) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto DEUTSCHES KREBSFORSCHUNGSZENTRUM Germania Contributo UE Nessun dato Indirizzo Im Neuenheimer Feld 280 HEIDELBERG Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato ASSOCIATION POUR LA RECHERCHE ET LE DÉVELOPPEMENT DES MÉTHODES ET PROCESSUS INDUSTRIELS Francia Contributo UE Nessun dato Indirizzo 60 boulevard Saint-Michel PARIS Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato TEL-AVIV UNIVERSITY Israele Contributo UE Nessun dato Indirizzo Haim Levanon St. Ramat-Aviv 39040 TEL-AVIV Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato PATERSON INSTITUTE FOR CANCER RESEARCH CHRISTIE HOSPITAL NHS TRUST Regno Unito Contributo UE Nessun dato Indirizzo WILMSLOW ROAD MANCHESTER Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato INSTITUT CURIE Francia Contributo UE Nessun dato Indirizzo 26, RUE D'ULM PARIS Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato MEDICAL UNIVERSITY GRAZ Austria Contributo UE Nessun dato Indirizzo Auenbruggerplatz 25 GRAZ Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato THE UNIVERSITY OF MANCHESTER Regno Unito Contributo UE Nessun dato Indirizzo Oxford Road MANCHESTER Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato