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Risk assessment of new and emerging systemic iridoviral diseases for European fish and aquatic ecosystems

Objective

The proposed project aims to assess the threat of systemic iridoviruses to farmed and wild freshwater fish and amphibian wildlife in the EU. A major element will be experimental infection trials on a range of important European species of farmed and wild freshwater fish and wild amphibians to provide data needed for the assessment. This will include major farmed food species but also representative farmed ornamental fish species that are increasingly being produced in Europe and have long been speculated to be vectors of systemic iridoviruses. Several species of wild predator fish will be tested including European perch, which are highly susceptible to at least one exotic systemic iridovirus. Representative amphibians species will also be tested because wild populations appears to be seriously affected by systemic iridoviruses. Immunological diagnostic methods for the detection of systemic iridoviruses in tissues of naturally infected species will be developed to facilitate the characterization of the pathology and pathogenesis for each susceptible species and allow rapid diagnosis in the event of a future outbreak in EU. Molecular methods will be developed for the differentiation of systemic iridoviruses and thereby provide the means of differentiating the OIE notifiable and highly virulent isolates from the less potent isolates. Surveillance of disease in EU-produced and imported ornamental fish and pet or wild amphibians will be ducted to gain knowledge of the current presence of systemic iridoviruses and indicate the potential for the aquatic pet trade to be a route of introduction and spread. Applying epidemiological principles, a risk assessment model (RAM) will be developed to assess the potential pathways of spread and likely impact of those viruses showing greatest virulence in the experimental trials. Recommendations will be made to the Commission on future actions needed to prevent further incursion and spread of serious iridoviral diseases in the EU.

Call for proposal

FP6-2003-SSP-3
See other projects for this call

Funding Scheme

IP - Integrated Project

Coordinator

DANMARKS TEKNISKE UNIVERSITET
Address
Anker Engelundsvej 1, Building 101 A
Kgs Lyngby
Denmark

Participants (5)

ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLE VENEZIE
Italy
Address
Viale Dell'universita', 10
Legnaro
FINNISH FOOD SAFETY AUTHORITY
Finland
Address
Mustialankatu 3
Helsinki
VYZKUMNY USTAV VETERINARNIHO LEKARSTVI - VETERINARY RESEARCH INSTITUTE
Czechia
Address
Hudcova 70
Brno
FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSANSTALT FUER VIRUSKRANKHEITEN DER TIERE
Germany
Address
Boddenblick 5A
Greifswald - Insel Riems
THE SECRETARY OF STATE FOR ENVIRONMENT FOOD AND RURAL AFFAIRS ACTING THROUGH THE CENTRE FOR ENVIRONMENT, FISHERIES AND AQUACULTURE SCIENCE
United Kingdom
Address
Pakefield Road
Lowestoft