Obiettivo Recent experiments have shown that organic material in secondary organic aerosols (SOA) can polymerize leading to new high molecular weight compounds with mass up to 1000 Da. Such polymers are of concern regarding their potential adverse health effects and impact on air quality and climate. High molecular weight compounds have been found in ambient aerosols but their origin is unknown and their identification rudimentary. This project aims to apply and develop different sophisticated analytical methods to m easure high molecular weight compounds of this SOA polymer and to characterize its chemical and physical bulk parameters. In a joint measurement campaign at a smog chamber a combined effort will be undertaken to identify and characterize these polymers pro duced from different precursors which dominate in anthropogenic and biogenic emission sources. Simultaneously, these SOA polymers will be applied on-line to cell culture systems which are representative for the inner surface of airways and/or alveoli. Part icle-cell interactions will be investigated by ultrastructural and biochemical analyses. In addition, the cell cultures will be tested for the presence of reactive oxygen species and/or (pro)inflammatory proteins. A subset of the analytical tools will be d eployed to analyse ambient samples of which selected samples will be applied to cell cultures. The project will provide a basis to assess the risk of this new category of airborne contaminants to health as well as the importance of these polymers and the p olymerization process with respect to air quality and climate change. Since European research groups are at the forefront of this new scientific development, POLYSOA will significantly raise and strengthen the capabilities and scientific competitiveness of the European Research Area in this field. Campo scientifico natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural scienceschemical sciencespolymer sciencesengineering and technologyenvironmental engineeringair pollution engineeringnatural sciencesearth and related environmental sciencesatmospheric sciencesclimatologyclimatic changes Parole chiave Cardiovascular system Environmental health Nanotechnology SOA polymer secondary organic aerosol Programma(i) FP6-POLICIES - Policy support: Specific activities covering wider field of research under the Focusing and Integrating Community Research programme 2002-2006. Argomento(i) NEST-2003-2 - Insight activities Invito a presentare proposte FP6-2003-NEST-B-1 Vedi altri progetti per questo bando Meccanismo di finanziamento STREP - Specific Targeted Research Project Coordinatore PAUL SCHERRER INSTITUT Contributo UE Nessun dato Indirizzo VILLIGEN PSI Svizzera Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Partecipanti (4) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto CONSIGLIO NAZIONALE DELLE RICERCHE Italia Contributo UE Nessun dato Indirizzo Piazzale Aldo Moro 7 ROMA Mostra sulla mappa Costo totale Nessun dato JOHANNES GUTENBERG-UNIVERSITÄT MAINZ Germania Contributo UE Nessun dato Indirizzo Saarstr. 21 MAINZ Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato TECHNISCHE UNIVERSITAET WIEN Austria Contributo UE Nessun dato Indirizzo Karlsplatz 13 VIENNA Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato UNIVERSITÄT BERN Svizzera Contributo UE Nessun dato Indirizzo Hochschulstrasse 4 BERN Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato
