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Genomics to combat resistance against antibiotics in community-acquired LRTI in Europe

Objective

GRACE is a Network of Excellence focusing on the complex and controversial field of community-acquired lower respiratory tract infections (LRTI), which is one of the leading reasons for seeking medical care. The promiscuous use of antibiotics to treatmen t of LRTI accounts for a major part of the community burden of antibiotic use and contributes dramatically to the rising prevalence of resistance among major human pathogens. The overall objective of GRACE is to combat antimicrobial resistance through i ntegrating centres of research excellence and exploiting genomics in the investigation of community-acquired LRTI. Microbial and human genomics will be integrated with health sciences research consisting of clinical observational and intervention studies , health economics and health eduction to specifically change practice in managing community-acquired LRTI. GRACE is exceptional as it brings together investigators from basic laboratory sciences, clinical medicine, and health economics. In the jointly e xecuted research programme, 17 academic groups, spread accross 9 EU Member States and 5 SMEs will participate. GRACE will organise professional education, including web-based teaching and practical courses, through two leading European scientific societ ies (ESCMID and ERS) to disseminate the excellence of the programme. A high level of co-ordination will be obtained through a professionaly IT-supported and rigorous management structure, so as to achieve optimal synergy of the components of GRACE. We ai m to develop a genomic laboratory network in 8 European countries and a primary care research network in 11 European countries during the first 18 months of the project, and then to build on the infrastructure to create the jointly executed research prog ramme. The consortium will become a virtual "European LRTI Research Centre" potentially leading to a forum promoting research and good practice in the field of community-acquired LRTI.

Call for proposal

FP6-2004-LIFESCIHEALTH-5
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Coordinator

UNIVERSITEIT ANTWERPEN
Address
Prinsstraat 13
Antwerpen
Belgium

Participants (35)

LEIDS UNIVERSITAIR MEDISCH CENTRUM
Netherlands
Address
Albinusdreef 2
9600 Leiden
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
Address
University Offices, Wellington Square
Oxford
IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE
United Kingdom
Address
Exhibition Road
London
SMITTSKYDDSINSTITUTET
Sweden
Address
Nobels Väg 18
Solna
CARDIFF UNIVERSITY
United Kingdom
Address
30-36 Newport Road
Cardiff
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
Address
Universiteitsweg 100
85060 Utrecht
UNIVERSITY OF SOUTHAMPTON
United Kingdom
Address
University Road Highfield
Southampton
UNIVERSITY OF EAST ANGLIA
United Kingdom
Address
University Plain
Norwich
THE UNIVERSITY OF NOTTINGHAM
United Kingdom
Address
University Park
Nottingham
UNIVERSITA DEGLI STUDI DI MILANO
Italy
Address
Via Festa Del Perdono 7
Milano
RIGSHOSPITALET
Denmark
Address
Blegdamsvej 9
Copenhagen
KAROLINSKA INSTITUTET
Sweden
Address
Nobels Väg 16
Stockholm
TECHNISCHE UNIVERSITÄT KAISERSLAUTERN
Germany
Address
Gottlieb Daimlerstrasse
Kaiserslautern
INSTITUTO DE TECNOLOGIA QUIMICA E BIOLÓGICA
Portugal
Address
Av. Da República, Estação Agronómica Nacional
Oeiras
INSTITUTO DE SALUD CARLOS III
Spain
Address
Sinesio Delgado 6
Madrid
AMPTEC GMBH
Germany
Address
Koenigstr. 4A
Hamburg
PRIMAGEN HOLDING B.V.
Netherlands
Address
Meibergdreef 59
Amsterdam
MRC-HOLLAND
Netherlands
Address
Hudsonstraat 68
Amsterdam
PATHOFINDER
Netherlands
Address
Oxfordlaan 70
Maastricht
EUROPEAN SOCIETY FOR CLINICAL MICROBIOLOGY AND INFECTIOUS DISEASES
Germany
Address
Hainbuchenstrasse 65
11 31 Taufkirchen
EUROPEAN RESPIRATORY SOCIETY
Switzerland
Address
4, Avenue Sainte Luce
Lausanne
UNIVERSITY OF BIRMINGHAM
United Kingdom
Address
Edgbaston
Birmingham
CORIS BIOCONCEPT
Belgium
Address
Crealys Park, Rue Jean Sonet 4A
Gembloux
LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE
United Kingdom
Address
Keppel Street
London
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
Netherlands
Address
Meibergdreef 9 1105 Az
22700 Amsterdam
DRUG RESEARCH CENTRE LTD
Hungary
Address
Ady Endre Str. 12
Balatonfüred
FUNDACIO CLINIC PER A LA RECERCA BIOMEDICA
Spain
Address
Villarroel 170
Barcelona
CLINICAL RESEARCH ASSOCIATES AND CONSULTANTS
Slovakia
Address
Cukrova 14
Bratislava
MEDICAL UNIVERSITY OF LODZ
Poland
Address
4 Kosciuszki Ave.
Lodz
FUNDACIO PRIVADA SALUT DEL CONSORCI SANITARI DEL MARESME
Spain
Address
Carretera De Cirera S/n
Mataro
DIAKONIEKRANKENHAUS ROTENBURG GGMBH
Germany
Address
Elise-averdieck-str. 17
Rotenburg
LINKÖPINGS UNIVERSITET
Sweden
Address
Campus Valla
Linköping
ELY BRIDGE RESEARCH LTD
United Kingdom
Address
23 Mill Road Ely
Cardiff
FUNDACION PRIVADA SEMFYC
Spain
Address
Portaferrissa 8 Ppal
Barcelona
SOCIEDAD ESPANOLA DE MEDICINA DE FAMILIA Y COMUNITARIA
Spain
Address
Portaferrissa 8 Ppal
Barcelona