Objetivo Legumes, particularly pea, are valuable sources of human/animal food. However their yield and quality is constrained by diseases. This project aims to characterise novel disease resistance mechanisms in pea (Pisum sativum) to powdery mildew (Erysiphe pisi) and rust (Uromyces pisi) that can be devastating in regions of pea production. I will investigate inherent resistance and Induced Inaccesibility (II) and Accessibility (IA) to disease. At the cellular level, II and IA describe situations where early pat hogen attacks increase resistance or susceptibility, respectively, to later attacks. II is race non-specific, effective and persistent. Biochemical approaches and studies of differentially expressed gene candidates and proteins will provide insights into t he molecular basis of intra- and intercellular communication within and between tissues. This may reveal novel mechanisms of disease resistance for exploitation through plant breeding. As part of the project, we propose to investigate the involvement of nitric oxide in pea-powdery mildew and rust interaction dissecting its role as signalling molecule not only in inherent disease resistance but also in induced responses. Nitric oxide is emerging as a major signal in plant-pathogen interactions and there is need for spatio-temporal analyses of its role in economically important crop/pathogen interactions. Altogether this project offers a breakthrough in our understanding of the pathogenic interaction between pea and one of the most important constraints on productivity and quality. This should prove of great benefit in the current situation where most single gene controlled resistances to pathogens have been negated by evolution of pathogenic virulence. This has led to increasing reliance on fungicides that are expensive, difficult to apply and may pose threats to the environment and the consumer. There is an urgent need for novel and more durable forms of resistance to control disease effectively and safely. Ámbito científico agricultural sciencesagriculture, forestry, and fisheriesagricultureagronomyplant breeding Palabras clave Erysiphe pisi Uromyces pisi induced inaccesibilility legumes nitric oxide papilla pea Programa(s) FP6-MOBILITY - Human resources and Mobility in the specific programme for research, technological development and demonstration "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006 Tema(s) MOBILITY-4.1 - Marie Curie European Reintegration Grants (ERG) Convocatoria de propuestas FP6-2002-MOBILITY-11 Consulte otros proyectos de esta convocatoria Régimen de financiación ERG - Marie Curie actions-European Re-integration Grants Coordinador CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Aportación de la UE Sin datos Dirección C/ Serrano 117 MADRID España Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos
