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NOVEL SOLUTIONS FOR THE SUSTAINABLE CONTROL OF NEMATODES IN RUMINANTS

NOVEL SOLUTIONS FOR THE SUSTAINABLE CONTROL OF NEMATODES IN RUMINANTS

Objective

PARASOL focuses on gastro-intestinal nematode parasites of ruminants as they are the greatest threat to animal welfare and production, and since effective contributions can be made within three years. Current conventional methods for worm control involve repeated dosing of whole herds with synthetic anthelmintics but are unsustainable due to the food and environmental residues produced and promote the spread of anthelmintic resistance by failing to leave an untreated parasite refugium.

Effective chemical anthelmintics remain irreplaceable for worm control and their elimination is not practical on animal welfare and economic grounds. We will replace current practice with Targeted Selective Treatments, where only animals showing clinical symptoms or reduced productivity are given drugs. Animals with low worm burdens are symptomless and do not require treatment. We will assess several innovative methods, under various farming conditions, for identifying animals that require treatment, and produce and standardise tests for anthelmintic resistance to ensure that the drugs are effective. We will produce, by the end of the project, clear guidance and protocols for sustainable, low-input, user- and consumer-friendly nematode control.

In order to do this we will:
(1) assess the effect of targeted selective treatments on productivity, animal welfare and the spread of anthelmintic resistance genes under a range of farming conditions;
(2) determine the best methods of identifying animals and herds requiring anthelmintic intervention;
(3) standardise existing in vivo and in vitro tests for detecting anthelmintic resistance and develop new tests for where current ones are inadequate;
(4) optimise the efficacy and bio-availability of anthelmintics by modulating parasite P-glycoprotein detoxification systems; and
(5) communicate with farmers, veterinarians and advisors, to produce and disseminate guidance to ensure good uptake and implementation of the protocols produced.

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Coordinator

UNIVERSITEIT GENT

Address

Sint-Pietersnieuwstraat 25
Ghent

Belgium

Administrative Contact

Jozef VERCRUYSSE (Professor)

Participants (16)

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UNIVERSITY OF BATH

United Kingdom

UNIVERSITY OF BRISTOL

United Kingdom

STIFTUNG TIERAERZTLICHE HOCHSCHULE HANNOVER

Germany

SVERIGES LANTBRUKSUNIVERSITET

Sweden

MOREDUN RESEARCH INSTITUTE

United Kingdom

PARASITOLOGICAL INSTITUTE, SLOVAK ACADEMY OF SCIENCES

Slovakia

UNIVERSITY OF PRETORIA

South Africa

INSTITUT AGRONOMIQUE ET VÉTÉRINAIRE HASSAN II

Morocco

ARISTOTELIO PANEPISTIMIO THESSALONIKIS

Greece

UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II

Italy

INNOVIS LTD.

United Kingdom

NATIONAL WOOL GROWERS' ASSOCIATION

South Africa

SVANOVA BIOTECH AB

Sweden

PLANTAMEDIUM GMBH

Germany

FRAENZ & JAEGER GMBH

Germany

INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE

France

Project information

Grant agreement ID: 22851

  • Start date

    1 February 2006

  • End date

    30 April 2009

Funded under:

FP6-FOOD

  • Overall budget:

    € 3 877 833

  • EU contribution

    € 2 940 000

Coordinated by:

UNIVERSITEIT GENT

Belgium