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From sensation to action; moving towards advanced neural rehabilitation devices

Cel

Every basic movement requires that sensory information is available to the brain to generate appropriate movement commands. E.g. traumatic brain or spinal cord injury may result in lost sensation and motor functions in large parts of the body. Normal movement planning involves integration of information from multiple sensory modalities (e.g. visual, auditory, body orientation).

It will be important to understand how movement planning are effectuated based on multi-modality sensory events in awake, behaving animals to develop advanced motor or sensory rehabilitation technology for brain and spinal cord injured subjects. This project will assess how externally generated sensory stimuli (auditory and/or vibrotactile) affect behavioural association-response tasks (go/no-go and graded decision).

Secondly, the project will assess how artificially generated stimuli (vibrotactile) in the brain are sensed and reacted upon with and without the presence of a second sensory modality (auditory). In specific, the motor and sensory areas in the brain and peripheral sensory nerves related to forelimb movement/sensation will be interfaced using chronically implanted electrodes in rats.

This research is expected to provide results that are important for closed-loop rehabilitation devices in which,
- the signals recorded from the primary motor cortexin the brain is used as feed-forward control signals or,
- peripheral sensory information is used as feedback to the primary sensory cortex in the brain.

With this project, I will bring back expertise on chronic animal work and cortical recording techniques that will strengthen the European Research Area. The project will be carried out in collaboration with Dr. Patrick Rousche (University of Illinois at Chicago, USA) and Dr. Ken Yoshi da (Aalborg University, Denmark).

Zaproszenie do składania wniosków

FP6-2002-MOBILITY-6
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Koordynator

AALBORG UNIVERSITY
Wkład UE
Brak danych
Adres
Fredrik Bajers Vej 7 F
AALBORG
Dania

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