Obiettivo The two identical H atoms in the water molecule exist in two forms, with total nuclear spin number 1 (ortho isomer, o-) or zero (para isomer, p-) respectively. The equilibrium o/p ratio at RT is 3:1, but it has been recently shown that mixtures enriched i n one isomeric species can be obtained by selective adsorption onto aluminum oxide or activated coal surfaces. The quantitation of the o/p ratio has been possible by means of submillimeter IR spectroscopy.The consequences of this breakthrough are not yet fully appreciated. Indeed, due to the central role of water for life on Earth, the availability of water with altered o/p ratio can be of paramount importance and may open new, highly innovative applications in a number of fields, ranging from medicine, biology, chemistry to earth sciences, meteorology etc. This Adventure project aims at exploring the feasibility of some of these exciting applications.To this end, it will deal with:1) Optimising the separation methods of o-and p-water isomers;2) Developing new methods of identification and quantitation of o- and p-water; in particular, NMR approaches will be developed (17O,1H);3) Understanding (and controlling) the determinants responsible for o- and p-isomers' lifetimes;4) Characterizing the physico-chemical properties of the two isomers and studying natural and artificial systems displaying non-equilibrium o/p ratios. The different properties of the o- and p- isomers may open new adventures in the study of the spatial distribution in water containing objects, ranging from inorganic objects to biological systems, and the o/p ratio could be used as a sensor to assess functionality changes in material science and in living systems.5) Designing new and innovative contrast agents for MRI, based on the peculiar properties of o- and p-water:a) generating "negative" images by using NMR-silent p-water, andb) producing 13C-hyperpolarized contrast agents by addition of p-water to suitable substrates Campo scientifico natural sciencesearth and related environmental sciencesatmospheric sciencesmeteorologyengineering and technologyenvironmental engineeringenergy and fuelsfossil energycoalengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsnatural scienceschemical sciencesphysical chemistrynatural sciencesphysical sciencesopticsspectroscopy Parole chiave Imaging Medical Science Material Imaging Programma(i) FP6-POLICIES - Policy support: Specific activities covering wider field of research under the Focusing and Integrating Community Research programme 2002-2006. Argomento(i) NEST-2003-1 - Adventure activities Invito a presentare proposte FP6-2003-NEST-A Vedi altri progetti per questo bando Meccanismo di finanziamento STREP - Specific Targeted Research Project Coordinatore UNIVERSITÀ DEGLI STUDI DI TORINO Contributo UE Nessun dato Indirizzo Via Verdi, 8 TORINO Italia Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Partecipanti (5) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLOPROTEINE PARAMAGNETICHE Italia Contributo UE Nessun dato Indirizzo Via Luigi Sacconi, 6 SESTO FIORENTINO Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato MOSCOW STATE UNIVERSITY Russia Contributo UE Nessun dato Indirizzo Leninskiye Gory MOSCOW Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato RUSSIAN ACADEMY INSTITUTE OF GENERAL PHYSICS, RUSSIAN ACADEMY OF SCIENCES Russia Contributo UE Nessun dato Indirizzo Vavilov str.38 MOSCOW Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato UNIVERSITE HENRI POINCARE NANCY 1 Francia Contributo UE Nessun dato Indirizzo rue Lionnois 24-30 NANCY Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato UNIVERSITÄT ZU KOELN-UNIVERSITÄTSKLINIKUM Germania Contributo UE Nessun dato Indirizzo Kerpener Strasse 62 KOELN Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato