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Molecular basis of antibiotic translocation

Objective

With increasing antibiotic resistance, the search for new drugs is one of the top priorities in our society. European groups have traditionally been strong in this field, but keeping a leading position needs a tremendous effort because of the complexity of the problems involved. The strength and originality is that we combine an original biophysical approach how to quantify translocation on a single molecular level with a new generation of computer programmes allowing now the modelling of transport.

In order to maximize the outcome of this novel approach both groups need urgently the feedback from microbiology. Without a close connection to real data this approach will be rather an academic problem and would never reach potential application. Here we went eve n a step further and include a main player in antibiotic drug design and a second SME on high throughput screening device. This will give a unique stimulation and a unique source of complementary expertise. This project will bridge the gap between this already existing collaboration to microbiology and pharmacology to transfer the knowledge into application. By embedding this research programme in a training initiative we also confer the pertinent skills to a large number of young researchers.

Our research-training programme addresses the following issues:
(1) Solving a scientific question related to combating antibiotic resistance (FP6 and FP7: Life)
(2) Bridging natural gaps through an interdisciplinary training for young researchers by spending a significant part of a training programme in other institutes, with industrial partners and in different countries of the EU.
(3) Open training programme and workshops to educate our fellows and external students

Call for proposal

FP6-2004-MOBILITY-1
See other projects for this call

Coordinator

JACOBS UNIVERSITY BREMEN GMBH
EU contribution
No data
Address
Campus Ring 1
BREMEN
Germany

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Participants (6)