Objective Recently, advances in modern imaging techniques, in combination with the availability of genetic tools has set the stage for detailed studies at the single cell level. Our experience has been that mechanisms underlying developmental processes are conserved in organisms ranging from nematodes, insects, mice and man. In this ToK we plan to join our efforts, approaches (molecular, cellular, developmental, evolutionary), know-how in various model-systems (nematodes, insects, mice) to gain insight aspects of their development.Our group (part of the Developmental and Functional Biology group of the IMBB) consists of principal investigators that are leaders in their field in Europe and whose laboratories have provided training to many researchers from Greece and abroad. We have joined our efforts to move our research forward through the development of a new competence of advanced imaging in live organisms; we consider this expertise essential and timely as it will provide us with a leading, competitive edge towards groups in the US and Japan. The need for this competence has stemmed from our training activities as part of the Greek Microscopy Network and by the realization that all of our groups - and the host institute as a whole- would collectively benefit tremendously from the establishment of live imaging techniques, an expertise lacking in our country altogether.Work towards developing and applying the new competence will be distributed among the following directions:a) mapping patterns of cell division, movement and differentiation in the growth zone of insects,b) monitoring Notch signalling in Drosophila and other insects,c) monitoring migrations in the mammalian central nervous system,d) studying the role of mammalian adhesion molecules in the nematode ande) identifying genes required for the sensory transduction and integration that forms the basis of learning and memory in the nematode. Fields of science natural sciencesbiological sciencesneurobiologynatural sciencesbiological sciencescell biologycell signalingnatural sciencesbiological sciencesdevelopmental biologynatural sciencesphysical sciencesopticsmicroscopynatural sciencesbiological scienceszoologyentomology Keywords Learning and Memory Neurogenesis Neuronal migration Programme(s) FP6-MOBILITY - Human resources and Mobility in the specific programme for research, technological development and demonstration "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006 Topic(s) MOBILITY-1.3 - Marie Curie Host Fellowships - Transfer of knowledge (TOK) Call for proposal FP6-2005-MOBILITY-3 See other projects for this call Funding Scheme TOK - Marie Curie actions-Transfer of Knowledge Coordinator FOUNDATION FOR RESEARCH AND TECHNOLOGY-HELLAS, INSTITUTE OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY EU contribution No data Address VASSILIKA VOUTON 1385 HERAKLION Greece See on map Links Website Opens in new window Total cost No data
