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Biomaterials for wound healing and tissue regeneration

Objective

The aim of the work is to manufacture novel biomaterials for wound and burns healing and tissue regeneration and characterise their mechanical, physical and physicochemical properties and evaluate their biocompatibility and performance in the required applications. In this project natural and natural/synthetic polymer hydrogels produced by cryopolymerisation will be used to design new materials for tissue regeneration. The existing know how in polymer chemistry, synthesis of activated carbons, protein biochemistry, cell biology and manufacturing of biomaterials, owned by the academic and industrial partners involved in this project, will be combined in order to develop and manufacture novel materials for efficient treatment of wounds and burns and with a potential for wider use in tissue scaffolding and regenerative medicine.

The objectives of the project are:
(i) to develop a new technology for production of super-macroporous polymer cryogels for wound healing and tissue regeneration;
(ii) to produce a number of biopolymer cryogels and evaluate their mechanical, physical and physicochemical properties;
(iii) to design a wound healing material based on polymer cryogels with incorporated activated carbon;
(iv) to design a composite polymer cryogel/activated carbon fibre wound dressing;
(v) to evaluate in vitro biocompatibility of the materials in (i)-(iv);
(vi) to test performance of the materials in (i)-(iv) on advanced 3D skin models;
(vii) to assess the potential of the materials in (i,ii) for cell growth and tissue regeneration.

These objectives will be achieved through the knowledge transfer activities between academic, medical and industrial partners involved in this project.

Call for proposal

FP6-2005-MOBILITY-3
See other projects for this call

Funding Scheme

TOK - Marie Curie actions-Transfer of Knowledge

Coordinator

UNIVERSITY OF BRIGHTON
Address
Mithras House, Lewes Road
Brighton
United Kingdom

Participants (10)

LUND UNIVERSITY
Sweden
Address
Paradisgatan 5C
117 Lund
PROTISTA BIOTECHNOLOGY AB
Sweden
Address
Ideon
Lund
BLOND-MCINDOE RESEARCH FOUNDATION
United Kingdom
Address
Queen Victoria Hospital, Holtye Road
East Grinstead
MAST CARBON TECHNOLOGY LTD
United Kingdom
Address
85 St Modwen Road
Plymouth
FACULTéS UNIVERSITAIRES NOTRE-DAME DE LA PAIX
Belgium
Address
Rue De Bruxelles, 61
Namur
STRATICELL SCREENING TECHNOLOGIES SA
Belgium
Address
14 Rue Lecomte
Namur
BRIGHTWAKE LIMITED
United Kingdom
Address
Sidings Road, Lowmoor Business Park
Kirkby-in-ashfield, Nottinghamshire
QUEEN VICTORIA HOSPITAL NHS FOUNDATION TRUST
United Kingdom
Address
Holtye Road
E Grinstead, W. Sussex
MAST CARBON INTERNATIONAL LTD
United Kingdom
Address
Henley Park
Guildford
CLINIMED LIMITED
United Kingdom
Address
Cavell House, Knaves Beech Way, Loudwater
High Wycombe