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Southern urals radiation risk research

Southern urals radiation risk research

Objective

The aim of the SOUL project is to quantify risks of late health effects associated with low-dose rate exposure to plutonium, strontium and external gamma radiation. This will be done by improving, updating and analysing dosimetric and health data for the Mayak worker cohort (MWC), the extended Techa River cohort (ETRC) and the Techa River offspring cohort (TROC). Key dosimetric elements include electron paramagnetic resonance (EPR) measurements of tooth enamel, photon spectra measurements, luminescence measurements of absorbed doses in bricks, measurements of strontium distributions in teeth, fluorescence in-situ hybridisation (FISH) measurements of chromosome aberrations, and modelling of internal doses of foetuses and infants. The dosimetric work aims to produce updated dose data bases Mayak Doses 2008 and Techa Doses 2008. In order to increase statistical precision and validity, the number of individuals in the cohorts will be extended, and information on vital status and cause of death will be updated. In the TROC, cancer and cardiovascular disorders will be studied as late health effects following exposure early in life. Non-cancer effects will be studied in the ETRC. The pathogenesis of lung cancer in the MWC will be studied in order to improve the current knowledge. The MWC will be used to study cancer incidence, and mortality and morbidity of circulatory diseases such as myocardial infarction and stroke. In the studies, initial feasibility analyses will be followed - if affirmative - by analyses that are based on longer follow-up and dosimetric data bases improved within the framework of SOUL. Although SOUL is expected to give significant input to the understanding of radiation risks, Southern Urals radiation risk research has to be tinued beyond the project mainly because a longer follow-up is needed to fully quantify lifetime risks. Part of the work in SOUL is dedicated to supporting such future analyses.

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Coordinator

HELMHOLTZ ZENTRUM MUENCHEN, DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT

Address

Lngolstaedter Landstrasse 1
Neuherberg

Germany

Administrative Contact

Jacob PETER (Dr)

Participants (15)

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HEALTH PROTECTION AGENCY

United Kingdom

URALSKY NAUCHNO-PRAKTICHESKY TSENTR RADIATSIONNOI MEDITSINY

Russia

SOUTHERN URALS BIOPHYSICS INSTITUTE

Russia

KAROLINSKA INSTITUTET

Sweden

GEOSPETZECOLOGIYA

Russia

ISTITUTO SUPERIORE DI SANITA

Italy

BUNDESAMT FUER STRAHLENSCHUTZ

Germany

ARISTOTELIO PANEPISTIMIO THESSALONIKIS

Greece

AKADEMISCH ZIEKENHUIS LEIDEN

Netherlands

WESTLAKES SCIENTIFIC CONSULTING LIMITED

United Kingdom

TECHNISCHE UNIVERSITAET MUENCHEN

Germany

INSTITUTE OF METAL PHYSICS, RUSSIAN ACADEMY OF SCIENCES

Russia

UNIVERSITA DEGLI STUDI DI PALERMO

Italy

UNIVERSITY OF FLORIDA

United States

EBERHARD KARLS UNIVERSITAET TUEBINGEN

Germany

Project information

Grant agreement ID: 516478

  • Start date

    1 August 2005

  • End date

    31 December 2009

Funded under:

FP6-EURATOM-RADPROT

  • Overall budget:

    € 11 444 946

  • EU contribution

    € 6 800 000

Coordinated by:

HELMHOLTZ ZENTRUM MUENCHEN, DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT

Germany