Skip to main content

Minimizing Activity and Dose with Enhanced Image quality by Radiopharmaceutical Administrations

Objective

MADEIRA aims to improve 3D nuclear medical imaging technologies significantly. Achievements will be made in terms of reduction of radiation exposure, increase of spatial and temporal resolution. In consequence, the applied techniques will offer better and more detailed pictures for diagnosis obtained with less exposure to radioactivity. Due to the introduction of new diagnostic procedures such as CT, PET and SPECT, the individual dose caused by medical exposures rapidly grew in the last years. This is especially a subject to radiation protection for nuclear medical diagnosis since in this case radiopharmaceuticals are administered to the patient meaning not only a radiation exposure to the unhealthy tissue but also to the healthy tissue of large parts of the body. When dealing with cancer any improvement in the efficacy and availability of proper diagnostic procedures turns out into a benefit for the patients. Early diagnosis reduces mortality and other serious implications like loss of quality of living or high therapy costs. Diagnosis that provides information about - activity of the cancerous tissue - in what 3D region of the cancer and - what kind of cancer to be treated in each specific case is very important. 3D functional nuclear medicine imaging satisfies the above requirements. Especially the combination of today’s systems with CT scanners allows simultaneous acquisition of anatomical and functional information. MADEIRA will improve the efficacy and safety of 3D PET and SPECT functional imaging by optimising the spatial resolution, the signal-to-noise ratio and the knowledge of the temporal variation of the radiopharmaceuticals’ uptake in and clearance from tumour and healthy tissues and evaluating the corresponding patient dose. By this approach to an optimized imaging procedure gaining more information per administered dose MADEIRA will especially reduce the dose to healthy tissue of the patient.

Call for proposal

FP7-Fission-2007
See other projects for this call

Coordinator

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Address
Ingolstadter Landstrasse 1
85764 Neuherberg
Germany
Activity type
Research Organisations
EU contribution
€ 663 673
Administrative Contact
Juergen Ertel (Dr.)

Participants (6)

MAX IV Laboratory, Lund University
Sweden
EU contribution
€ 337 490
Address
Paradisgatan 5C
22100 Lund
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Lennart Råstam (Prof.)
INSTITUT JOZEF STEFAN
Slovenia
EU contribution
€ 423 114
Address
Jamova 39
1000 Ljubljana
Activity type
Research Organisations
Administrative Contact
Jadran Lenarcic (Prof.)
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 460 778
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
Administrative Contact
Mar Garcia-Ferrer (Ms.)
Scivis wissenschaftliche Bildverarbeitung GmbH
Germany
EU contribution
€ 679 605
Address
Bertha-von-suttner-str, 5
37085 Göttingen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Gernot Ebel (Dr.)
UNIVERSITA DEGLI STUDI DI MILANO
Italy
EU contribution
€ 255 340
Address
Via Festa Del Perdono 7
20122 Milano
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Fortunato Laface (Mr.)
UNIVERSITY OF MICHIGAN THE REGENTS OF THE UNIVERSITY OF MICHIGAN
United States
Address
South Street 3003 1068
46109 1274 Ann Arbor
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Thomas Zdeba (Mr.)