The main objectives of this project are: 1) Perfection of growing technology of (Lux-Y1-x)AlO3:Ce crystals with 0.2 and 0.7 lutetium content in (Lu-Y) system. 2) Development of Gamma Camera and PET/CT detector prototypes based on (Lux-Y1-x)AlO3:Ce crystals. Research activities on the project will include: 1) Study the crystal optical properties and their dependence on technological factors. 2) Optimization of horizontal Bridgeman (HB) growing technology of (Lux-Y1-x)AlO3:Ce crystals with 0.2 and 0.7 lutetium content in (Lu-Y) system to increase the crystal transparency and light yield. 3) Gamma Camera and PET/CT detector design and prototyping. 4) Evaluation of detector prototypes. Expected result of the project will consist in development of significantly improved (Lux-Y(1-x))AlO3:Ce scintillation crystals opening the possibility for development of novel medical imaging instrumentation. Main expected fields of this material application are: 1) Nuclear medicine. 2) Environmental monitoring and well logging.