Cel The concept of a relationship between the structure and the toxic activity of chemical mutagens and carcinogens has been widely investigated. Structure-activity concepts have also been exploited to make safer chemicals. Whereas for academic purposes even studies based on biased data sets may provide useful information, the extensive regulatory use of (Q)SARs foreseen by e.g. REACH requires that the models fulfill severe quality criteria. Unfortunately, this ideal situation is not a common occurrence in toxicology. This proposal is aimed at organizing a debate among, and a Workshop of leading experts to critically review the situation of in the field of the (Q)SARs for mutagenicity and carcinogenicity, and to provide indications on hot topics issues to be further investigated. SCARLET is multidisciplinary and multisectorial. Regulators, scientists, problem holders, animal welfare experts, citizen organizations, and chemical industry will participate. Target is 40 participants; registration will be free to reach a wider participation. 6 fellowships will be given to young researchers. The workshop will be useful to cut barriers between scientific and societal areas. SCARLET will discuss an architecture to compare and integrate individual studies. Coordinators of EC projects will be invited, so that their results will be disseminated, providing a high resonance to the European research. This will also avoid repetition of studies, making optimal use of public money and identifying synergisms. Their EC projects will be a way to exploit recommendations from the workshop. The verifiable results will be the workshop, the internet site, a list of software and databases, the report with recommendations for use of computer-based methods in carcinogenicity, mutagenicity and genotoxicity. A paper summarizing the discussion at the workshop will be submitted to a scientific journal. Dziedzina nauki natural sciencescomputer and information sciencessoftwarenatural sciencescomputer and information sciencesinternetnatural sciencescomputer and information sciencesdatabasesmedical and health sciencesbasic medicinetoxicologysocial scienceslaw Słowa kluczowe Carcinogenicity QSAR genotoxicity mutagenicity Program(-y) FP6-POLICIES - Policy support: Specific activities covering wider field of research under the Focusing and Integrating Community Research programme 2002-2006. Temat(-y) POLICIES-2.2 - Public health issues, including epidemiology contributing to disease prevention and responses to emerging rare and communicable diseases, allergies, procedures for secure blood and organ donations, non-animal test methods Zaproszenie do składania wniosków FP6-2005-SSP-5-A Zobacz inne projekty w ramach tego zaproszenia System finansowania SSA - Specific Support Action Koordynator ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI Wkład UE Brak danych Adres Via Eritrea 62 MILAN Włochy Zobacz na mapie Linki Strona internetowa Opens in new window Koszt całkowity Brak danych Uczestnicy (3) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko CHRISTOPH HELMA Niemcy Wkład UE Brak danych Adres Stadtstr. 19 FREIBURG Zobacz na mapie Linki Strona internetowa Opens in new window Koszt całkowity Brak danych NESTEC S.A. Szwajcaria Wkład UE Brak danych Adres Avenue Nestle' 55 VEVEY Zobacz na mapie Linki Strona internetowa Opens in new window Koszt całkowity Brak danych ISTITUTO SUPERIORE DI SANITA' Włochy Wkład UE Brak danych Adres Viale Regina Elena 299 ROME Zobacz na mapie Linki Strona internetowa Opens in new window Koszt całkowity Brak danych
