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New Antimicrobials

Objective

Antibacterial resistance is spreading globally at an alarming rate and continues to increase. New potent antibacterial agents and therapies are therefore continually needed. In recent years, new antibacterial compounds have mainly been additions to the existing classes of drugs and very few new structures have been developed. Pharmaceutical industry has little interest in developing novel structures due to high investment and low profit expectancy. The derivatives of existing drugs typically raise bacterial resistance much faster than completely new compounds. To overcome the chronic problem of antibiotic resistance, totally new compounds and approaches are required, involving collaboration of researchers from various sectors and disciplines, as well as high societal investments. The NAM project aims to confront these problems by intense collaboration between industry and academia. The project aims at i) discovery of totally new antibacterial compounds from one of the richest untapped natural sources, endophytes, ii) development of totally new approaches based on antimicrobial host defense peptides, iii) research on the mechanisms of action of antimicrobial compounds. Through these objectives novel anti-infective agents can potentially be applied to the battle against bacterial resistance. NAM is a highly multidisciplinary consortium, consisting of groups in biology, chemistry, biophysics, biochemistry, microbiology and biotechnology. It consists of two companies (one SME and a large biotech company), and three university research laboratories in four different countries within the EU.

Field of science

  • /natural sciences/biological sciences/microbiology/bacteriology
  • /natural sciences/biological sciences/biophysics
  • /natural sciences/biological sciences/biochemistry
  • /natural sciences/biological sciences/microbiology
  • /medical and health sciences/basic medicine/pharmacology and pharmacy/drug resistance/antibiotic resistance

Call for proposal

FP7-PEOPLE-2007-3-1-IAPP
See other projects for this call

Funding Scheme

MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP)

Coordinator

OULUN YLIOPISTO
Address
Pentti Kaiteran Katu 1
90014 Oulu
Finland
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 434 701
Administrative Contact
Leila Risteli (Dr.)

Participants (4)

NOVOZYMES A/S
Denmark
EU contribution
€ 445 853
Address
Krogshoejvej 36
2880 Bagsvaerd
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Hans-Henrik Kristensen Høgenhaug (Dr.)
NOVAMASS OY
Finland
EU contribution
€ 89 756
Address
Kiviharjuntie 11
90220 Oulu
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Juha Saharinen (Dr.)
UNIVERSITA DEGLI STUDI DI TRIESTE
Italy
EU contribution
€ 250 350
Address
Piazzale Europa 1
34127 Trieste
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Alessandra Deschmann (Ms.)
UNIVERSITATSKLINIKUM BONN
Germany
EU contribution
€ 205 032
Address
Venusberg-campus 1
53127 Bonn
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Melanie Ottawa (Ms.)