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Infrafrontier The European infrastructure for phenotyping and archiving of model mammalian genomes

Objective

Medically related Life Sciences use the mouse as a model system to understand the molecular basis of health and disease in humans (>95% similarity of genes in humans and mice). An essential task for Biomedical Sciences in the 21st century will be the functional analysis of mouse models for every gene in the mammalian genome. The major bottlenecks identified by the user community will be proper characterization (Mouse Clinics), archiving and dissemination of mouse disease models to the research laboratories. The current capacities, governance structures and funding strategies of existing infrastructures will not be able to serve the upcoming urgent needs. Thus it is imperative to organise and establish now an efficient distributed infrastructure for the phenotyping, archiving and dissemination of mouse models on a well concerted, large-scale and pan-European level. This will be a prerequisite for maintaining Europe’s leading role in the functional annotation of the mouse genome. Infrafrontier will guarantee the accessibility of mouse models and will be essential to facilitate their exploitation. Infrafrontier integrates 15 European laboratories with exceptional track records to implement and run large-scale infrastructures. Infrafrontier builds on existing infrastructures under EMMA and EUMODIC and forms a coalition with a significant number of funding agencies to develop the prerequisites to a common European infrastructure. The Infrafrontier preparatory phase aims to organise a stable and sustainable infrastructure by 1) the identification of the most suitable legal form, 2) developing a business plan based on a sustainable funding concept, 3) reaching a legal agreement between all partners and 4) providing a strategic plan for the construction phase. Infrafrontier will therefore give Europe a leading position in the worldwide competition on resources and knowledge for medically relevant mouse models by providing a user-driven platform.

Field of science

  • /social sciences/economics and business/economics/sustainable economy
  • /natural sciences/biological sciences/genetics and heredity/genome

Call for proposal

FP7-INFRASTRUCTURES-2007-1
See other projects for this call

Funding Scheme

CP-CSA-Infra - Combination of CP and CSA

Coordinator

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Address
Ingolstadter Landstrasse 1
85764 Neuherberg
Germany
Activity type
Research Organisations
EU contribution
€ 2 534 199,24
Administrative Contact
Jürgen Ertel (Dr.)

Participants (28)

MEDICAL RESEARCH COUNCIL
United Kingdom
EU contribution
€ 464 075,95
Address
North Star Avenue Polaris House 2 Floor David Phillips Building
SN2 1FL Swindon
Activity type
Research Organisations
Administrative Contact
Deborah Stephens (Ms.)
CONSIGLIO NAZIONALE DELLE RICERCHE
Italy
EU contribution
€ 333 249,50
Address
Piazzale Aldo Moro 7
00185 Roma
Activity type
Research Organisations
Administrative Contact
Glauco Tocchini-Valentini (Prof.)
CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE
France
EU contribution
€ 121 288,10
Address
Rue Laurent Fries 1
67404 Illkirch Graffenstaden
Activity type
Research Organisations
Administrative Contact
Katell Schaeffer (Ms.)
GENOME RESEARCH LIMITED
United Kingdom
EU contribution
€ 71 527,50
Address
The Gibbs Building, Euston Road 215
NW1 2BE London
Activity type
Research Organisations
Administrative Contact
David Neil Davison (Mr.)
BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING
Greece
EU contribution
€ 125 282,40
Address
Fleming Street 34
16672 Vari-athens
Activity type
Research Organisations
Administrative Contact
Athina Ikonomidou (Ms.)
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 78 110
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Riitta Ljungström (Ms.)
FUNDACAO CALOUSTE GULBENKIAN
Portugal
EU contribution
€ 40 927,50
Address
Avenida Berna 45
1000 Lisboa
Activity type
Research Organisations
Administrative Contact
José Mário Leite (Dr.)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France
EU contribution
€ 157 557,98
Address
Rue Michel Ange 3
75794 Paris
Activity type
Research Organisations
Administrative Contact
Josette Roger (Ms.)
UNIVERSIDAD AUTONOMA DE BARCELONA
Spain
EU contribution
€ 81 563,09
Address
Calle Campus Universitario Sn Cerdanyola V
08290 Cerdanyola Del Valles
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Katja Schustakowitz (Ms.)
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 78 881,24
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
Administrative Contact
María Del Mar García (Ms.)
OULUN YLIOPISTO
Finland
EU contribution
€ 70 620
Address
Pentti Kaiteran Katu 1
90014 Oulu
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Leila Risteli (Dr.)
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
EU contribution
€ 68 287,50
Address
Meyerhofstrasse 1
69117 Heidelberg
Activity type
Research Organisations
Administrative Contact
Keith Williamson (Mr.)
HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH
Germany
EU contribution
€ 178 072,50
Address
Inhoffenstrasse 7
38124 Braunschweig
Activity type
Research Organisations
Administrative Contact
Michael Strätz (Dr.)
KOBENHAVNS UNIVERSITET
Denmark
EU contribution
€ 64 467,50
Address
Norregade 10
1165 Kobenhavn
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ivan Kristoffersen (Mr.)
GENIKI GRAMMATIA EREVNAS KAI TECHNOLOGIAS
Greece
Address
Mesogeion Avenue 14-18
11510 Athens
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Aikaterini Galanou (Ms.)
HERMANN VON HELMHOLTZ-GEMEINSCHAFT DEUTSCHER FORSCHUNGSZENTREN EV
Germany
Address
Ahrstrasse 45
53175 Bonn
Activity type
Research Organisations
Administrative Contact
Tania Lieckweg (Dr.)
BUNDESMINISTERIUM FUER BILDUNG UND FORSCHUNG
Germany
Address
Heinemannstrasse 2
53175 Bonn
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Ingrid Zwoch
VETENSKAPSRADET - SWEDISH RESEARCH COUNCIL
Sweden
EU contribution
€ 7 222,50
Address
Vastra Jarnvagsgatan 3
111 64 Stockholm
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Tove Andersson (Dr.)
DEPARTAMENT DE SALUT - GENERALITAT DE CATALUNYA
Spain
EU contribution
€ 7 222,50
Address
Trav. De Les Corts (Pavelló Ave Maria) 131-159
08028 Barcelona
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Ramon Maspons (Dr.)
FUNDACION PARQUE CIENTIFICO DE MADRID-FPCM
Spain
EU contribution
€ 7 222,50
Address
Calle Faraday 7 Edificio Claid
28049 Madrid
Activity type
Research Organisations
Administrative Contact
Ana Martinez (Dr.)
FUNDACION PARA EL CONOCIMIENTO MADRIMASD
Spain
EU contribution
€ 7 222,50
Address
Paseo De Recoletos, Num. 14
28014 Madrid
Activity type
Other
Administrative Contact
José De La Sota (Mr.)
BIOCEV z.s.p.o.
Czechia
EU contribution
€ 1 500
Address
K Vyzkumnym Ustavum 1/1083
14220 Praha
Activity type
Research Organisations
Administrative Contact
Jan Rajnoch (Dr.)
VETERINAERMEDIZINISCHE UNIVERSITAET WIEN
Austria
EU contribution
€ 1 500
Address
Veterinaerplatz 1
1210 Vienna
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Wolfgang Kuenzel (Prof.)
Toronto Centre for Phenogenomics Inc.
Canada
Address
Orde Street 25
M5T 3H7 Toronto
Activity type
Research Organisations
Administrative Contact
Michael Gottlieb (Mr.)
MINISTRY OF EDUCATION YOUTH AND SPORTS
Czechia
Address
Karmelitska 7
11812 Prague
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Gabriela Vlckova (Ms.)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
Administrative Contact
Karine Lanini (Ms.)
MINISTERO DELLA SALUTE
Italy
Address
Via Giorgio Ribotta 5
00144 Roma
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Massimo Casciello (Dr.)
USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE
Czechia
Address
Videnska 1083
142 20 Praha 4
Activity type
Research Organisations
Administrative Contact
Radislav Sedlacek (Dr.)