Objective
In this proposal, we have mobilized a critical mass of expertise to investigate, on a Europe-wide scale, the natural history and pathophysiology of rare inherited diseases affecting important structures of the kidney. The project will use and develop multiple models (in vitro and in vivo) with the aim to develop preventive, diagnostic and therapeutic interventions that should alleviate the burden of these diseases, particularly in children. A central part of the proposal is the creation of a European registry and a network of genetic laboratories to foster a tight interaction between physicians and researchers, promote clinical and basic research, and ensure the efficient dissemination of knowledge. By increasing our knowledge of these rare diseases, the EUNEFRON project will also yield new insights into basic processes relevant for the general population (progression of renal disease, blood pressure control, prevention of renal stones, effect of gender and ageing, etc…), the complex relationship between different nephron segments, and the multi-systemic involvement of renal diseases.
Fields of science
Call for proposal
FP7-HEALTH-2007-A
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Funding Scheme
CP-FP - Small or medium-scale focused research project
Coordinator
1348 Louvain La Neuve
Belgium
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Participants (9)
75654 Paris
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8000 Aarhus C
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6525 XZ Nijmegen
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10117 Berlin
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8006 Zurich
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20132 Milano
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Participation ended
WC1E 6BT London
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3000 Leuven
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WC1N 3JH London
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