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Resolve Chronic Inflammation and Achieve Healthy Aging by Understanding Non-regenerative Repair

Objective

RESOLVE has been outlined to better understand the regulatory networks that control the devel-opmental processes in organ repair and to identify mechanisms which cause the termination of regu-lar organ development leading to fibroproliferative wound healing. Fibroproliferative wound healing represents a major pathology in elderly people shifting regular organ development into progressive organ fibrosis with complete loss of organ function. Based on the identification of valuated molecu-lar targets of fibroproliferative repair, RESOLVE aims to create suitable treatment strategies to achieve healthy ageing in the elderly. In doing so, RESOLVE will create a significant impact on life quality of elderly people. RESOLVE’s outcomes will strengthen the competitiveness of European science and biotechnology industry and contribute to cost saving strategies in the health care sector. RESOLVE’s structured scientific approach combines as yet fragmented fields of research using model organisms which represent (a) different forms of wound healing, (b) different human diseases and (c) different genetic backgrounds, guaranteeing social and scientific relevance, modularity of re-search and the integration of existing biological knowledge, technical expertise and medical experi-ence. In addition, sequential generation of data during improvement or worsening ensures clinical relevance and leads to a stringent exploitation strategy. The sustainable outcomes of RESOLVE’s efforts will be: (A) the urgently needed diagnostic tool for fibroproliferative wound healing in various organs, (B) highly valuable transgenic animals offering test systems for fibroproliferative wound healing, and (C) a characterization of compounds capable of interfering with targets involved in fibroprolifera-tive repair.

Field of science

  • /medical and health sciences/basic medicine/pathology

Call for proposal

FP7-HEALTH-2007-A
See other projects for this call

Funding Scheme

CP-IP - Large-scale integrating project

Coordinator

MEDIZINISCHE UNIVERSITAET WIEN
Address
Spitalgasse 23
1090 Wien
Austria
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 2 816 568,44
Administrative Contact
Lutz-Henning Block (Prof.)

Participants (13)

INTEGROMICS SL ITG
Spain
EU contribution
€ 528 465
Address
Avenida De Innovacion Granada Parque Tecnologia Ciencas De La Salud 1 Bic
18100 Armilla -Granada
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Isabel Cuesta (Dr.)
POLITECNICO DI TORINO
Italy
EU contribution
€ 317 275
Address
Corso Duca Degli Abruzzi 24
10129 Torino
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Angela Pozzo (Dr.)
UNIVERSITA DEGLI STUDI DI VERONA
Italy
EU contribution
€ 445 051,68
Address
Via Dell Artigliere 8
37129 Verona
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Enrico Cazzaroli (Dr.)
BIOTALENTUM TUDASFEJLESZTO KFT
Hungary
EU contribution
€ 676 953
Address
Aulich Lajos Utca 26
2100 Goedoello
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Zsuzsanna Hericsne Buda
INSTYTUT MEDYCYNY WSI IM WITOLDA CHODZKI
Poland
EU contribution
€ 399 920
Address
Jaczewskiego 2
20950 Lublin
Activity type
Research Organisations
Administrative Contact
Marcin Golec (Dr.)
BEN-GURION UNIVERSITY OF THE NEGEV
Israel
EU contribution
€ 456 628
Address
.
84105 Beer Sheva
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Daphna Tripto (Ms.)
UNIVERSITE CATHOLIQUE DE LOUVAIN
Belgium
EU contribution
€ 573 135
Address
Place De L Universite 1
1348 Louvain La Neuve
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Francois Huaux (Prof.)
UNIVERSITY OF BRISTOL
United Kingdom
EU contribution
€ 841 441
Address
Beacon House Queens Road
BS8 1QU Bristol
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Vince Boyle (Mr.)
AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH
Austria
EU contribution
€ 2 427 159,88
Address
Giefinggasse 4
1210 Wien
Activity type
Research Organisations
Administrative Contact
Christa Noehammer (Dr.)
BRIGITTE ROHNER

Participation ended

Austria
EU contribution
€ 37 278,84
Address
Grosse Schiffgasse 5 23
1020 Wien
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Brigitte Rohner (Ms.)
CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL
Germany
EU contribution
€ 537 046
Address
Olshausenstrasse 40
24118 Kiel
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ingmar Schmidt (Dr.)
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 298 886
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
Administrative Contact
Maria Del Mar Garcia (Ms.)
PUNKT INTERNATIONAL GMBH
Austria
EU contribution
€ 333 906,16
Address
Lowengasse 45/2
1030 Wien
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Brigitte Rohner (Ms.)