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Integrated Structural Biology Infrastructure

Integrated Structural Biology Infrastructure

Objective

Structural biology in the next two decades aims to integrate structural knowledge at different resolution levels into specific cellular contexts, with a temporal component, to underpin biomedical sciences. This challenge requires the seamless integration of techniques providing information in different resolution ranges. INSTRUCT will link the information obtained by the major structural biology methods with state-of-the art cell biology techniques to provide a dynamic picture of key cellular processes at all scales. Major technology advances, from high throughput methods in protein production, though NMR and X-ray crystallography to electron microscopy mean that major investment in infrastructure is required to maintain European competitiveness. The preparatory phase of INSTRUCT will forge a pan-European structure comprising a number of Core Centres, with broad infrastructure provision, an appropriate number of Associate Centres, with complimentary expertise and establish the mechanisms for establishing National Access Holder Communities of users and rules for access. The development of cutting-edge infrastructure will be energised by a focus on a few key biomedical questions and environment problems. There will be strong involvement of European industry and SMEs, by both direct collaboration on feasibility studies and by consultation; this will arise naturally as the requirements for high precision innovative instrumentation will challenge European industry to improve their capabilities and the use of the facilities for industrial research will strengthen Europe’s industrial competitiveness in particular in bio-pharma companies. The project will include a training program based on relevant interdisciplinary expertise. A major aim of the preparatory phase will be to establish the mechanisms, financial and legal, by which major funding bodies can work together to provide a coherent European infrastructure with wide European access.

Coordinator

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD

Address

Wellington Square University Offices
Ox1 2jd Oxford

United Kingdom

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 2 724 097

Administrative Contact

Stephen Conway (Dr.)

Participants (13)

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CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE

France

EU Contribution

€ 274 398

EUROPEAN MOLECULAR BIOLOGY LABORATORY

Germany

EU Contribution

€ 313 898

CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE

Italy

EU Contribution

€ 316 098

WEIZMANN INSTITUTE OF SCIENCE

Israel

EU Contribution

€ 235 599

MEDICAL RESEARCH COUNCIL

United Kingdom

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS

France

THE ISRAELI MINISTRY OF SCIENCE, CULTURE AND SPORT

Israel

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV

Germany

EU Contribution

€ 516 198

BUNDESMINISTERIUM FUER BILDUNG UND FORSCHUNG

Germany

BRUKER BIOSPIN GMBH

Germany

EU Contribution

€ 60 900

CONSIGLIO NAZIONALE DELLE RICERCHE

Italy

UNIVERSITY OF YORK

United Kingdom

EU Contribution

€ 58 800

COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

France

Project information

Grant agreement ID: 211252

Status

Closed project

  • Start date

    1 April 2008

  • End date

    31 March 2011

Funded under:

FP7-INFRASTRUCTURES

  • Overall budget:

    € 7 543 170,80

  • EU contribution

    € 4 499 988

Coordinated by:

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD

United Kingdom