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Bottom-up Resolution of Functional Enantiomers from Self-Organised Monolayers

Objective

The high throughput identification of resolution systems for industrially important chiral chemicals will be approached using the bottom-up hierarchichal assembly from self-organised chirally nanostructured surfaces and the “Dutch resolution” family method to isolation of enantiomers. Molecular modelling, surface science, supramolecular chemistry and the critically important resolving library design will be used in synergy to develop systems which separate enantiomers and which can be patterned and miniaturised. The preparation of chiral surfaces and the knowledge of chiral discrimination phenomena at the nanoscale will be exploited to use them to template the formation of diastereomers, which in turn will lead to the formation of crystals (whose composition will be determined) containing pure enantiomers. The project’s end goal is a rapid method for the identification of resolving systems for optically active compounds, and would constitute a leap forward for the area.

Field of science

  • /social sciences/sociology/social problems/ageism
  • /engineering and technology/materials engineering/crystals

Call for proposal

FP7-NMP-2007-SMALL-1
See other projects for this call

Funding Scheme

CP-FP - Small or medium-scale focused research project

Coordinator

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Address
Calle Serrano 117
28006 Madrid
Spain
Activity type
Research Organisations
EU contribution
€ 433 876
Administrative Contact
Alberto Sereno Alvarez (Mr.)

Participants (5)

THE UNIVERSITY OF LIVERPOOL
United Kingdom
EU contribution
€ 478 220
Address
Brownlow Hill 765 Foundation Building
L69 7ZX Liverpool
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Colin Cooper (Mr.)
SYNCOM BV
Netherlands
EU contribution
€ 356 025
Address
Kadijk 3
9747 AT Groningen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Karin De Jager (Ms.)
KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium
EU contribution
€ 478 230
Address
Oude Markt 13
3000 Leuven
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Maria Vereeken (Ms.)
UNIVERSITE DE MONS
Belgium
EU contribution
€ 373 000
Address
Place Du Parc 20
7000 Mons
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Dany Vince (Mr.)
TECHNISCHE UNIVERSITEIT EINDHOVEN
Netherlands
EU contribution
€ 313 609
Address
Groene Loper 3
5612 AE Eindhoven
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Albert Schenning (Dr.)