CORDIS
EU research results

CORDIS

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Prospective cohort studies of children with substantial medical diagnostic exposure

Project information

Grant agreement ID: 212839

Status

Closed project

  • Start date

    1 September 2008

  • End date

    30 November 2009

Funded under:

FP7-EURATOM-FISSION

  • Overall budget:

    € 361 022,40

  • EU contribution

    € 279 931

Coordinated by:

CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER

France

Objective

The growing use of diagnostic X-rays and of high-dose techniques (CT, interventions) in children and adolescents is a topic of concern in radiological protection. Studies of other populations indicate that children are generally more sensitive to health effects of radiation than adults. In addition, children have a longer life-span to express any radiation-related health effect and, because of their smaller mass children, may receive higher doses to specific organs from these procedures if examination protocols are not adapted. Procedures of particular concern include: the use of CT in children (which delivers doses that are substantially greater than those from conventional X-rays); interventional cardiology, in which fluoroscopy is used to guide small instruments such as catheters through blood vessels (which, if repeated, can deliver doses of several hundred mGy to specific organs); and the use of repeated X-rays for monitoring respiratory, cardiac and digestive pathologies in premature babies (for repeated procedures, cumulative doses range up to a few mGy – and premature babies could be particularly sensitive to radiation induced diseases). Because the health effects of these low doses of radiation are expected to be relatively small, trans-national collaborative studies are needed to ensure sufficient statistical power to study these effects. In this project we seek support to assemble a critical mass of scientists involved in the study of medical radiation exposures and health effects of radiation dispersed throughout Europe with the aim of: ● Assessing the feasibility of establishing prospective trans-national cohorts suitable for long term follow up (including evaluation of the statistical power of the study) ● If the feasibility is demonstrated: - Making recommendations for future research needs including populations suitable for long term follow-up; - Developing specific project proposals, including study protocols and procedures for follow-up.
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Coordinator

CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER

Address

150 Cours Albert Thomas
69372 Lyon Cedex 08

France

Activity type

Other

EU Contribution

€ 114 735,24

Administrative Contact

Olaf Kelm (Dr.)

Participants (8)

SATEILYTURVAKESKUS

Finland

EU Contribution

€ 10 000

KAROLINSKA INSTITUTET

Sweden

EU Contribution

€ 10 000

UNIVERSITY OF NEWCASTLE UPON TYNE

United Kingdom

EU Contribution

€ 10 000

FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL

Spain

EU Contribution

€ 95 195,76

INSTITUT GUSTAVE ROUSSY

France

EU Contribution

€ 10 000

KRAEFTENS BEKAEMPELSE

Denmark

EU Contribution

€ 10 000

STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS

Netherlands

EU Contribution

€ 10 000

UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ

Germany

EU Contribution

€ 10 000

Project information

Grant agreement ID: 212839

Status

Closed project

  • Start date

    1 September 2008

  • End date

    30 November 2009

Funded under:

FP7-EURATOM-FISSION

  • Overall budget:

    € 361 022,40

  • EU contribution

    € 279 931

Coordinated by:

CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER

France