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Natural Products and related Redox Catalysts: Basic Research and Applications in Medicine and Agriculture

Natural Products and related Redox Catalysts: Basic Research and Applications in Medicine and Agriculture

Objective

Intracellular redox processes are pivotal for cell survival and proliferation. Redox active natural products, enzymes and their mimics may therefore be considered as regulators of various cellular processes which may, for instance, control inflammatory processes, cancer formation and proliferation, but also bacterial, fungal and microbial growth. It is now apparent that redox control exerted by such natural and synthetic products may be used for prevention and therapy in Medicine and for the development of ‘green’ pesticides in Agriculture. This training network will study chemical, biochemical and biological aspects of the modulation of cellular redox balances by selected natural agents and their mimics. It relies on expertise of 10 full and 7 associated partners (1 SME) in a range of scientific disciplines, including synthetic, analytical, biological and pharmaceutical chemistry, biochemistry, cell biology, microbiology, cancer research and agricultural research. The network will address 4 36-month work packages (WP): A WP on natural antioxidants, inflammation and cancer; a WP studying intracellular redox control and signalling events triggered by external redox agents; a WP on green antibiotics and pesticides from plants and fungi; a WP on redox catalysts as agents selective against cancer and inflammatory cells. The network will provide interdisciplinary training for 4 experienced and 10 early stage researchers, all of which will acquire expertise in 3 or more of scientific disciplines. Each researcher will develop a training portfolio when joining the network. All early stage researchers are expected to obtain international recognised PhD degrees. In addition to intensive scientific training at various host institutes, there will be a framework programme offering training in science related matters and soft skills, such as logical and ethical aspects of research, IP, patenting and commercialisation, communication skills and cultural and gender issues.
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Coordinator

UNIVERSITAT DES SAARLANDES

Address

Campus
66123 Saarbrucken

Germany

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 526 087,22

Administrative Contact

Vera Siegmund (Dr.)

Participants (9)

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RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN

Germany

EU Contribution

€ 192 359,20

UNIVERSIDADE DE AVEIRO

Portugal

EU Contribution

€ 194 993,70

DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

Germany

EU Contribution

€ 192 359,20

ECOSPRAY LIMITED

United Kingdom

EU Contribution

€ 358 703,41

THE UNIVERSITY OF EXETER

United Kingdom

EU Contribution

€ 376 315,49

RECHERCHES SCIENTIFIQUES LUXEMBOURG ASBL

Luxembourg

EU Contribution

€ 206 800

UNIVERSITE DE LORRAINE

France

EU Contribution

€ 349 332,49

UNIVERSITE PARIS DESCARTES

France

EU Contribution

€ 196 340,09

URSAPHARM Arzneimittel GmbH

Germany

EU Contribution

€ 192 359,20

Project information

Grant agreement ID: 215009

Status

Closed project

  • Start date

    1 December 2008

  • End date

    30 November 2012

Funded under:

FP7-PEOPLE

  • Overall budget:

    € 2 785 650

  • EU contribution

    € 2 785 650

Coordinated by:

UNIVERSITAT DES SAARLANDES

Germany