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Exploring the glycosylation process during infection

Objective

Cellular Glycosylation is a finely tuned process that is very suscpetible in changes due to environmental stimuli. We have preliminary data showing that intestinal infections in mice and rats are capable in changing the glycosylation profile of intestinal glycoproteins. We speculate that this could be due to a translational regulation of glycosyltransferases. Hence, we would like to use RT-PCR and quantiative proteomic to identify specific glycosyltransferases affected by the infection cycle.
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Coordinator

GOETEBORGS UNIVERSITET

Address

Vasaparken
405 30 Goeteborg

Sweden

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 67 069,89

Administrative Contact

Ludde Edgren (Dr.)

Participants (1)

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NATIONAL UNIVERSITY OF IRELAND GALWAY

Ireland

EU Contribution

€ 32 930,11

Project information

Grant agreement ID: 205302

Status

Closed project

  • Start date

    21 January 2008

  • End date

    9 May 2012

Funded under:

FP7-PEOPLE

  • Overall budget:

    € 100 000

  • EU contribution

    € 100 000

Coordinated by:

GOETEBORGS UNIVERSITET

Sweden

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