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Metagenomics for bioexploration - Tools and application

Metagenomics for bioexploration - Tools and application

Objective

This proposal will (further) develop and apply metagenomics tools to access the enzymatic potential borne in the cryptic biota of selected natural habitats, in particular target soil-related and aquatic ones. In the light of the environmental relevance of chitins and lignins (as natural compounds recalcitrant to degradation) and halogenated aliphatic and aromatic compounds (anthropogenic recalcitrant compounds), the enzymatic activities that we will target are functions able to degrade these compounds. A database of gene functions will be established and maintained. Next to its great relevance to environmental biotechnology including bioremediation, a spin-off of the work will be the discovery of novel biocatalytic functions of industrial relevance. We will in particular address the catabolic potential that is encoded by the mobilome, the collective pool of mobile genetic elements in the microbiota. We will further apply high-throughput (454-based) sequencing to rapidly unravel the metabolic complement in this mobile gene pool. The project brings together a suite of 15 contractors across Europe, encompassing 21 laboratories spread over 11 copuntries and including 4 SMEs. Most of the partners are renowned laboratories which have vast experience in metagenomics of environmental samples, biotechnology, enzymology, bioinformatics, the mobilome, waste management and bioremediation and enzyme production.

Coordinator

RIJKSUNIVERSITEIT GRONINGEN

Address

Broerstraat 5
9712cp Groningen

Netherlands

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 876 780

Participants (17)

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RIJKSUNIVERSITEIT GRONINGEN

Netherlands

EU Contribution

€ 350 000

KOBENHAVNS UNIVERSITET

Denmark

EU Contribution

€ 386 400

SODERTORNS HOGSKOLA

Sweden

EU Contribution

€ 334 760

THE UNIVERSITY OF WARWICK

United Kingdom

EU Contribution

€ 389 000

WAGENINGEN UNIVERSITY

Netherlands

EU Contribution

€ 389 080

ECOLE CENTRALE DE LYON

France

EU Contribution

€ 482 500

UNIVERSITAET BIELEFELD

Germany

EU Contribution

€ 417 600

JULIUS KUHN-INSTITUT BUNDESFORSCHUNGSINSTITUT FUR KULTURPFLANZEN

Germany

EU Contribution

€ 250 000

KATHOLIEKE UNIVERSITEIT LEUVEN

Belgium

EU Contribution

€ 395 000

TEKNOLOGIAN TUTKIMUSKESKUS VTT

Finland

EU Contribution

€ 395 000

UNIVERSITE CATHOLIQUE DE LOUVAIN

Belgium

EU Contribution

€ 338 400

UNIVERSITA DEGLI STUDI DELL'INSUBRIA

Italy

EU Contribution

€ 291 000

UNIVERZA V LJUBLJANI

Slovenia

EU Contribution

€ 201 000

UNIVERSIDAD NACIONAL DE LA PLATA

Argentina

EU Contribution

€ 165 000

BioDetection Systems B.V.

Netherlands

EU Contribution

€ 190 000

Whitby Seafoods Ltd

United Kingdom

EU Contribution

€ 70 000

INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE

France

EU Contribution

€ 78 471

Project information

Grant agreement ID: 222625

Status

Closed project

  • Start date

    1 May 2009

  • End date

    30 April 2014

Funded under:

FP7-KBBE

  • Overall budget:

    € 8 065 047

  • EU contribution

    € 5 999 991

Coordinated by:

RIJKSUNIVERSITEIT GRONINGEN

Netherlands