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Aquired Environmental Epigenetics Advances: from Arabidopsis to maize

Objective

This proposal, entitled “Acquired Environmental Epigenetics Advances: from Arabidopsis to maize” (acronym: AENEAS), aims to assess the impact of environmental conditions on epigenetic states in the model plant Arabidopsis thaliana and then transfer knowledge to maize (Zea mays): an important European crop. Advances in understanding the detailed mechanisms of epialleles formation in response to environmental cues and their heritable maintenance in a model plant such as Arabidopsis will be the starting objective of the AENEAS proposal. To this end, we will focus on three epigenetic regulatory pathways, which have been well characterized for their interaction with environmental signals in mediating changes into the epigenome. They are: the autonomous, the small RNA and the CpG methylation pathways. The outcome of this research activity will be a road map for plant environmental epigenetics, necessary for further progress of the basic research in this area and for the transfer of the knowledge to crop plants. Concomitantly, the constitution of an “Environmental Epigenetics platform” for maize, will start with the development of tools indispensable for the shift of epigenetic research from Arabidopsis to maize. This will be achieved by the functional characterization of maize mutants for epi-regulators belonging to the three pathways studied in Arabidopsis. The tools will comprise: maize epi-regulator mutants, their targets, and information about their interaction with environmental cues for epialleles formation and inheritance throughout generations. It is our opinion that the deliverables from AENEAS will be the “progenitors” for the next-generation of breeding programs, based on the exploitation of the environmental-induced epigenetics variability. In addition, we will conduct a comparative genomics analysis of data arising from the project to generate comparative models for environmental epigenomics in two evolutionary distinct species such as Arabidopsis and maize.

Call for proposal

FP7-KBBE-2008-2B
See other projects for this call

Funding Scheme

CP-FP - Small or medium-scale focused research project

Coordinator

UNIVERSITA DEGLI STUDI DI PADOVA
Address
Via 8 Febbraio 2
35122 Padova
Italy
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 372 598
Administrative Contact
Giuseppe Zanin (Prof.)

Participants (7)

CONSIGLIO PER LA RICERCA IN AGRICOLTURA E L'ANALISI DELL'ECONOMIA AGRARIA
Italy
EU contribution
€ 321 403
Address
Via Po 14
00198 Roma
Activity type
Research Organisations
Administrative Contact
Vincenzo Rossi (Dr.)
THE UNIVERSITY OF WARWICK
United Kingdom
EU contribution
€ 506 059
Address
Kirby Corner Road - University House
CV4 8UW Coventry
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Trevor Brown (Mr.)
UNIVERSITE DE GENEVE
Switzerland
EU contribution
€ 356 500
Address
Rue Du General Dufour 24
1211 Geneve
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Jerzy Paszkowski (Prof.)
JOHN INNES CENTRE
United Kingdom
EU contribution
€ 396 000
Address
Norwich Research Park Colney
NR4 7UH Norwich
Activity type
Research Organisations
Administrative Contact
Mary Anderson (Dr.)
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU contribution
€ 317 312
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Edna Murphy (Ms.)
Klinik Max Planck Institut für Psychiatrie
Germany
EU contribution
€ 456 329
Address
Hofgartenstrasse 8
80539 Muenchen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Patrice Wegener (Mr.)
BIOGEMMA
France
EU contribution
€ 266 662
Address
Rue E. Colonne 1
75001 Paris
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Catherine Guichard (Dr.)