Skip to main content

Developing minimally invasive, tools and technologies for high throughput, low cost molecular assays for the early diagnosis of schizophrenia and other psychiatric disorders

Objective

Schizophrenia and bipolar affective disorder are a major burden to affected individuals and their families and to society at large. These two severe mental illnesses affect at least 2% of the population worldwide, and whilst 50% of sufferers do not receive adequate treatment, they cost hundreds of billions in healthcare provision, treatments and lost earnings. The current diagnosis of schizophrenia (and bipolar disorder etc.) is rather subjective, not only because of the complex spectrum of symptoms and their similarity to other mental disorders, but also due to the lack of empirical disease markers. This result in long delays (up to 1-3 years) before appropriate therapeutics is prescribed to first episode schizophrenics. Early treatment is associated with greatly improved patient outcomes. There is therefore a major unmet clinical need for empirical diagnostic tests for high throughput screening of biological fluids that would enable early and accurate diagnosis of schizophrenia and related disorders. The identification of specific biomarkers for mental disorders would revolutionise the clinical management of affected individuals. Biomarkers will help in the identification of disease sub-types, aid in predicting and monitoring treatment response and compliance, and identify novel drug targets. If such biomarkers can be found in readily accessible body fluids they open up the possibility of developing new early or pre-symptomatic diagnostics and/or treatments to improve outcomes or even prevent disease. The objective of our project is to identify biomarkers of disease and develop a diagnostic assay panel/tool for the high throughput screening of biological samples for clinical research. Moreover this platform will be utilised by SMEs for drug design and development for mental disorders research into new animal models for mental dirders and identifying biomarkers for other mental disorders

Field of science

  • /medical and health sciences/clinical medicine/psychiatry/schizophrenia

Call for proposal

FP7-HEALTH-2007-B
See other projects for this call

Funding Scheme

CP-TP - Collaborative Project targeted to a special group (such as SMEs)

Coordinator

PSYNOVA NEUROTECH LTD
Address
St John S Innovation Centre, Cowley Road -
CB4 0WS Cambridge
United Kingdom
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 373 354
Administrative Contact
Barbara Baron (Ms.)

Participants (8)

THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU contribution
€ 463 290
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Dawn Barker (Ms.)
ZENTRALINSTITUT FUER SEELISCHE GESUNDHEIT
Germany
EU contribution
€ 360 387
Address
Square J 5
68159 Mannheim
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Simone Fuchs (Ms.)
WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER
Germany
EU contribution
€ 360 387
Address
Schlossplatz 2
48149 Munster
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Karl-Heinz Runde (Mr.)
EDI Experimentelle Diagnostische Immunologie GmbH
Germany
EU contribution
€ 301 300
Address
Aspenhaustrasse
72770 Reutlingen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Thomas Joos (Dr.)
PERA INNOVATION LIMITED
United Kingdom
EU contribution
€ 175 220
Address
Innovation Park, Nottingham Road
LE13 OPB Melton Mowbray, Leicestershire
Activity type
Research Organisations
Administrative Contact
David Cartlidge (Mr.)
NATIONAL INSTITUTE FOR BIOPROCESSING RESEARCH AND TRAINING LIMITED
Ireland
EU contribution
€ 206 050
Address
Fosters Avenue Mount Merrion
4 Blackrock Dublin
Activity type
Research Organisations
Administrative Contact
Pauline Rudd (Prof.)
STORKBIO
Estonia
EU contribution
€ 147 056
Address
Laki 25
12915 Tallinn
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Kristi Kurg (Ms.)
MYRIAD RBM INC CORPORATION
United States
EU contribution
€ 370 644
Address
Duval Road 3300
TX 78759 Austin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Sam Labrie (Mr.)