Objective The CoMoFarm project will establish high-yielding production systems for pharmaceutical and industrial proteins based on plants, plant tissue and plant cells. The aim is to develop systems in which both the production host and the product itself show consistent yield and quality. The project will include a comparison of four alternative systems – hydroponic plants, root cultures, moss and suspension cells, and will involve the evaluation of different species, strain and process optimization, scale-up, downstream processing, protein characterization and process evaluation in terms of regulatory compliance. As well as furthering the development of an emerging production technology, the project will incorporate numerous innovative elements such as in-process monitoring and automation of environmental parameters to maintain a consistent environment and optimize protein yield and homogeneity, novel downstream processing technologies and innovative bioreactor and hydroponic designs to maintain plant health and ensure production according to good manufacturing practice. This project will have an immense impact on the biopharmaceuticals industry, by allowing SMEs interested in molecular farming to develop plant-made pharmaceuticals without worrying about regulatory constraints or poor investment prospects. This will go a long way to establishing molecular farming as a feasible industry within Europe, and will open new revenue streams for companies currently not interested in (or aware of) molecular farming, e.g. horticulture companies and nurseries. The cost of drugs will also begin to fall, which will positively re-enforce the benefits of plants and lead to greater growth in the market. Fields of science agricultural sciencesagriculture, forestry, and fisheriesagricultureagronomyplant protectionengineering and technologyenvironmental biotechnologybioremediationbioreactorsmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsagricultural sciencesagriculture, forestry, and fisheriesagriculturehorticulture Keywords automated protein production systems downstream processing non-invasive monitoring plant-based production platforms Programme(s) FP7-KBBE - Specific Programme "Cooperation": Food, Agriculture and Biotechnology Topic(s) KBBE-2008-3-1-05 - Development of fermentor-like applications and other plant-based containment systems for molecular farming Call for proposal FP7-KBBE-2008-2B See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV EU contribution € 828 617,00 Address HANSASTRASSE 27C 80686 Munchen Germany See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Research Organisations Administrative Contact Maximilian Steiert (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (9) Sort alphabetically Sort by EU Contribution Expand all Collapse all ZURCHER HOCHSCHULE FUR ANGEWANDTE WISSENSCHAFTEN Switzerland EU contribution € 58 659,00 Address GERTRUDSTRASSE 15 8401 Winterthur See on map Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Higher or Secondary Education Establishments Administrative Contact Dieter Eibl (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data TEKNOLOGIAN TUTKIMUSKESKUS VTT Finland EU contribution € 315 450,00 Address TEKNIIKANTIE 4 A 02044 VTT ESPOO See on map Activity type Research Organisations Administrative Contact Irmeli Koskinen (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN Germany EU contribution € 232 320,00 Address TEMPLERGRABEN 55 52062 Aachen See on map Region Nordrhein-Westfalen Köln Städteregion Aachen Activity type Higher or Secondary Education Establishments Administrative Contact Ernst Schmachtenberg (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ST GEORGE'S HOSPITAL MEDICAL SCHOOL United Kingdom EU contribution € 438 399,00 Address CRANMER TERRACE SW17 0RE London See on map Region London Inner London — West Wandsworth Activity type Higher or Secondary Education Establishments Administrative Contact Paul Craven (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data FORSCHUNGSZENTRUM JULICH GMBH Germany EU contribution € 251 972,00 Address WILHELM JOHNEN STRASSE 52428 Julich See on map Region Nordrhein-Westfalen Köln Düren Activity type Research Organisations Administrative Contact Petra Insberg (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data GREENOVATION BIOTECH GMBH Germany EU contribution € 326 370,00 Address BOTZINGER STRASSE 29B 79111 FREIBURG See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Danielle Pueschel (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Dow AgroSciences LLC United States EU contribution No data Address Zionsville Road 9330 46268-1054 INDIANAPOLIS See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Ronald Maciak (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ADOLF KUHNER AG Switzerland EU contribution € 154 710,00 Address DINKELBERGSTRASSE 1 4127 BIRSFELDEN See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Tibor Anderlei (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data STICHTING WAGENINGEN RESEARCH Netherlands EU contribution € 228 300,00 Address DROEVENDAALSESTEEG 4 6708 PB Wageningen See on map Region Oost-Nederland Gelderland Veluwe Activity type Research Organisations Administrative Contact Leny Versteeg-Brouwer (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data