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Collaborative Oncological Gene-environment Study

Ziel

The overarching goal of COGS is to identify individuals with an increased risk of breast, ovary and prostate cancer. Furthermore, we will evaluate the effect of inherited genetic variation on tumour characteristics and clinical outcome. We will do this through quantifying the role of genetic and environmental/lifestyle risk in the largest data set ever generated. In all, we will include over 200,000 individuals in the COGS project. We will use detailed knowledge of the architecture of genetic susceptibility and interactions with environmental/lifestyle factors which will result in much more accurate individual risk prediction and improved intervention strategies. We are taking advantage of a unique possibility by incorporating seven existing consortia into one large project – COGS. Members of these consortia have collaborated successfully over the past years and results have been presented in world leading scientific journals such as Nature, Nature Genetics and Journal of the National Cancer Institute. These papers reflect that collaboration has been ongoing and that is has so far been very successful. We will also build on an existing European Commission project, TRANSBIG, thus adding value to already spent money. Results generated through COGS will lead to an improved understanding of the biological processes that underlie carcinogenesis, that in turn could guide new therapeutic strategies. Results will also lead to the development of new tests for risk prediction for breast, ovarian and prostate cancer.

Wissenschaftliches Gebiet

  • /Medizin- und Gesundheitswissenschaften/Klinische Medizin/Onkologie/Krebs/Prostatakrebs
  • /Medizin- und Gesundheitswissenschaften/Klinische Medizin/Onkologie/Krebs/Brustkrebs

Aufforderung zur Vorschlagseinreichung

FP7-HEALTH-2007-B
Andere Projekte für diesen Aufruf anzeigen

Finanzierungsplan

CP-IP - Large-scale integrating project
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Koordinator

KAROLINSKA INSTITUTET
Adresse
Nobels Vag 5
17177 Stockholm
Schweden
Aktivitätstyp
Higher or Secondary Education Establishments
EU-Beitrag
€ 1 301 573,17
Kontakt Verwaltung
Agneta Haeggstroem (Ms.)

Beteiligte (15)

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU-Beitrag
€ 3 796 030,40
Adresse
Trinity Lane The Old Schools
CB2 1TN Cambridge
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Keith Cann (Mr.)
QUEENSLAND INSTITUTE OF MEDICAL RESEARCH
Australien
Adresse
Herston Road, 300
QLD 4006 Herston
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Bronwyn Dunphy (Ms.)
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Deutschland
EU-Beitrag
€ 545 487,25
Adresse
Im Neuenheimer Feld 280
69120 Heidelberg
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Bettina Crispin (Ms.)
FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III
Spanien
EU-Beitrag
€ 2 300 650,68
Adresse
Calle Melchor Fernandez Almagro 3
28029 Madrid
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Juan José Collazo Nieto (Mr.)
MAX IV Laboratory, Lund University
Schweden
EU-Beitrag
€ 201 534
Adresse
Paradisgatan 5C
22100 Lund
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Susanne André (Ms.)
HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYMÄ
Finnland
EU-Beitrag
€ 201 471,60
Adresse
Stenbackinkatu 9
00029 Helsinki
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Mari Frostell (Ms.)
STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS
Niederlande
EU-Beitrag
€ 1 087 739,60
Adresse
Plesmanlaan 121
1066 CX Amsterdam
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Henri Van Luenen (Dr.)
FOUNDATION FOR GENOMICS & POPULATION HEALTH
United Kingdom
EU-Beitrag
€ 490 132
Adresse
Worts Causeway 2
CB1 8RN Cambridge
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Carol Lyon (Ms.)
KRAEFTENS BEKAEMPELSE
Dänemark
EU-Beitrag
€ 519 662,80
Adresse
Strandboulevarden 49
2100 Koebenhavn
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Claus Skytte Rasmussen (Mr.)
BREAST INTERNATIONAL GROUP - AISBL
Belgien
EU-Beitrag
€ 42 882,30
Adresse
Boulevard De Waterloo 121
1000 Bruxelles
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Livia Meirsman (Ms.)
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL
United Kingdom
EU-Beitrag
€ 600 674,80
Adresse
Old Brompton Road 123
SW7 3RP London
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Donna Conway (Ms.)
CENTRE DE LUTTE CONTRE LE CANCER LEON BERARD
Frankreich
EU-Beitrag
€ 136 884
Adresse
Rue Laennec 28
69373 Lyon
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Marina Rousseau-Tsangiris (Dr.)
University College London
United Kingdom
EU-Beitrag
€ 170 906,40
Adresse
Gower Street
WC1E 6BT London
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Greta Borg-Carbott (Ms.)
CANCER COUNCIL VICTORIA
Australien
Adresse
615 St Kilda Road
3004 Melbourne Victoria
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Priscilla Hinds (Ms.)
THE UNIVERSITY OF WARWICK
United Kingdom
EU-Beitrag
€ 319 872
Adresse
Kirby Corner Road - University House
CV4 8UW Coventry
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Peter Hedges (Dr.)