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Chromatin diseases: from basic mechanisms to therapy

Ziel

The scope of this ITN is to promote research and training in the field of chromatin diseases. Chromatin diseases (CD) are genetic pathologies resulting from mutations in structural components of chromatin or in enzymes that biochemically modify chromatin, altering chromatin status and thereby causing drastic effects on gene expression. CD frequency ranges from very rare to quite common pathologies; so far for the vast majority of them no treatment is as yet available. Molecular studies on these pathologies thus have a twofold value: to shed light on the intricate interplays between different levels of control of gene expression acting in the mammalian nucleus and to pave the way toward new and more effective strategies to approach the treatment of this increasing class of diseases. Our students will take advantage of the integrated approach on multilayered gene regulation, the multidisciplinary nature and the cutting-edge methodologies, which are an integral part of this proposal. We thus expect to provide a framework for the very high-level training of young researchers, receiving a strong backgrounds in molecular, cellular and developmental biology, genomics, bioinformatics, chromatin biology and epigenetics. Furthermore, they will develop expertise in many cutting edge methodologies and tools, such as imaging, high throughput gene technologies, ChIP. As a result, the ESRs will be highly competitive in performing independent research in various areas of biology and will represent a new breed of scientists trained in contemporary post-genomic biology using advanced technological tools to tackle human disease.

Aufforderung zur Vorschlagseinreichung

FP7-PEOPLE-ITN-2008
Andere Projekte für diesen Aufruf anzeigen

Koordinator

CONSIGLIO NAZIONALE DELLE RICERCHE
Adresse
Piazzale Aldo Moro 7
00185 Roma
Italien

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Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Antonio Baldini (Prof.)
EU-Beitrag
€ 564 827

Beteiligte (10)

UNIVERSITE DE LA MEDITERRANEE D'AIX-MARSEILLE II

Beteiligung beendet

Frankreich
Adresse
Boulevard Charles Livon, Jardin Du Pharo 58
13284 Marseille

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Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Celine Damon (Ms.)
BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING
Griechenland
EU-Beitrag
€ 371 880
Adresse
Fleming Street 34
16672 Vari-athens

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Aktivitätstyp
Research Organisations
Kontakt Verwaltung
George Kollias (Dr.)
THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU-Beitrag
€ 219 751
Adresse
Trinity Lane The Old Schools
CB2 1TN Cambridge

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Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Edna Murphy (Ms.)
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
EU-Beitrag
€ 213 151
Adresse
Wellington Square University Offices
OX1 2JD Oxford

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Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Lynne Hughson (Ms.)
FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE
Spanien
EU-Beitrag
€ 380 355
Adresse
Avenida Gran Via Hospitalet 199-203
08908 L'hospitalet De Llobregat

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Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Victoria Cochrane (Ms.)
UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA
Italien
EU-Beitrag
€ 212 351
Adresse
Via Universita 4
41121 Modena

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Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Sebastiano Calandra Buonaura (Prof.)
UNIVERSITA DEGLI STUDI DELL'INSUBRIA
Italien
EU-Beitrag
€ 205 751
Adresse
Via Ravasi 2
21100 Varese

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Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Adriana Jacona (Mr.)
UNIVERSITE D'AIX MARSEILLE
Frankreich
EU-Beitrag
€ 206 452
Adresse
Boulevard Charles Livon 58 Le Pharo
13284 Marseille

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Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Celine Damon (Ms.)
DIAGENODE
Belgien
EU-Beitrag
€ 200 309
Adresse
Rue Du Bois Saint Jean 3 Liege Park Science
4102 Seraing

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Aktivitätstyp
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt Verwaltung
Leon Etienne (Mr.)
UCL Elizabeth Garrett Anderson Institute for Women’s Health

Beteiligung beendet

United Kingdom
Adresse
Gower Street
WC1E 6BT London

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Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Greta Borg-Carbott (Ms.)