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New tools and approaches to control Porcine Reproductive and Respiratory Syndrome (PRRS) in the EU and Asia

Objective

Porcine reproductive and respiratory syndrome virus (PRRSV) is the major cause of reproductive and respiratory problems in pigs worldwide. Controlling this disease is a top priority in pig producing countries. Due to mutations at a high frequency, new variants of the virus appear that are no longer effectively controlled by the commercial vaccines. In addition, highly virulent variants emerge, leading to high losses. With regard to animal welfare and agricultural economics, there is an urgent need to control PRRS. Furthermore, the abusive use of antibiotics to control PRRSV-associated respiratory problems may lead to resistance that may endanger public health. PoRRSCon is an initiative of 14 partners originating from Europe and Asia with strong expertises in virology and immunology. They are doing frontline research on PRRSV and/or vaccine development. Two of these partners are leading European pharmaceutical companies that will guide the consortium in the direction of exploitable results. By joining their strengths they have an ideal position to be successful in one of the most difficult challenges in pig health, controlling PRRS. To reach this final goal, the following objectives are forwarded:(i) characterize genetically and antigenically current PRRSV isolates in Europe and Asia, (ii) have a better understanding of the complex pathogenesis of PRRSV infections, immune response against PRRSV and immune modulation by PRRSV, (iii) define the genetic base of PRRSV virulence, (iv) identify PRRSV proteins and domains on these viral proteins that are involved in the induction of the immunity against PRRSV and in the immune modulation of PRRSV, (v) develop new generation, efficacious and safe marker vaccines that can be adapted to temporary changes and geographical differences and (vi) develop DIVA assays that allow to differentiate infected from vaccinated animals. At the end, it will be possible to set up a control strategy by combining marker vaccines with DIVA assays

Fields of science

Programme(s)

Topic(s)

Call for proposal

FP7-KBBE-2009-3
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Funding Scheme

CP-FP-SICA - Small/medium-scale focused research project for specific cooperation actions dedicated to international cooperation partner countries(SICA)

Coordinator

UNIVERSITEIT GENT
Address
Sint Pietersnieuwstraat 25
9000 Gent
Belgium

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Saskia Vanden Broeck (Ms.)
Links
EU contribution
€ 461 100

Participants (15)

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 259 700
Address
Calle Serrano 117
28006 Madrid

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Activity type
Research Organisations
Administrative Contact
Carlos Manuel Abad Ruiz (Mr.)
Links
FUNDACIO CENTRE DE RECERCA EN SANITAT ANIMAL CRESA
Spain
EU contribution
€ 199 728
Address
Universidad Autonoma De Barcelona Edifici Cresa
08193 Barcelona

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Activity type
Research Organisations
Administrative Contact
Silvia Pratsavall (Ms.)
Links
EUROFINS INGENASA SA
Spain
EU contribution
€ 200 070
Address
Avenida Institucion Libre De La Ensenaza 41
28037 Madrid

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Rodriguez Maria Jose (Ms.)
Links
PARCO TECNOLOGICO PADANO S.R.L.
Italy
EU contribution
€ 159 980
Address
Via Einstein - Localita Cascina Codazza
26900 Lodi

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Gianluca Carenzo (Dr.)
Links
EIDGENOESSISCHES DEPARTEMENT FUER WIRTSCHAFT, BILDUNG UND FORSCHUNG

Participation ended

Switzerland
Address
Bundeshaus Ost
3003 Bern
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Caroline De St. Simon (Ms.)
Links
DANMARKS TEKNISKE UNIVERSITET
Denmark
EU contribution
€ 259 600
Address
Anker Engelunds Vej 101
2800 Kongens Lyngby

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Lars Erik Lars (Dr.)
Links
PANSTWOWY INSTYTUT WETERYNARYJNY - PANSTWOWY INSTYTUT BADAWCZY
Poland
EU contribution
€ 199 999
Address
Partyzantow 57
24100 Pulawy

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Activity type
Research Organisations
Administrative Contact
Tomasz Stadejek (Dr.)
Links
THE UNIVERSITY OF EDINBURGH
United Kingdom
EU contribution
€ 159 905
Address
Old College, South Bridge
EH8 9YL Edinburgh

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Angela Noble (Ms.)
Links
Food and Environment Research Agency
United Kingdom
EU contribution
€ 259 859
Address
Area 1a, Nobel House, Smith Square 17
SW1P 3JR London

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Lucinda Cranham (Ms.)
Links
STICHTING WAGENINGEN RESEARCH
Netherlands
EU contribution
€ 259 990
Address
Droevendaalsesteeg 4
6708 PB Wageningen

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Activity type
Research Organisations
Administrative Contact
Annemarie Rebel (Dr.)
Links
Shanghai Veterinary Research Institute - Chinese Academy of Agricultural Sciences
China
EU contribution
€ 128 200
Address
Ziyue Road 518
200241 Shanghai

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Activity type
Research Organisations
Administrative Contact
Shishan Yuan (Dr.)
Links
MINISTRY OF AGRICULTURE AND RURAL DEVELOPMENT
Vietnam
EU contribution
€ 97 725
Address
Lane 78, Giai Phong 15
844 Hanoi

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Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Van Long Nguyen (Dr.)
Links
BOEHRINGER INGELHEIM VETMEDICA GMBH
Germany
EU contribution
€ 13 200
Address
Binger Strasse 173
55218 Ingelheim

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Vicky Fachinger (Dr.)
Links
CHINA AGRICULTURAL UNIVERSITY
China
EU contribution
€ 80 000
Address
Yuanmingyuan Xilu 2 Haidian District
100193 Beijing

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ruying Gao (Ms.)
Links
EIDGENOESSISCHES DEPARTEMENT DES INNERN
Switzerland
EU contribution
€ 260 014
Address
Inselgasse 1
3003 Bern

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Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Caroline De St. Simon
Links

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Last update: 16 July 2019
Record number: 93024

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Permalink: https://cordis.europa.eu/project/id/245141

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