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Luminescent polymers for in vivo imaging of amyloid signatures

Luminescent polymers for in vivo imaging of amyloid signatures

Objective

In this project we seek to develop new smart imaging molecular tools for combating neurodegenerative diseases such as Alzheimer’s disease and prion diseases. Emphasis is put on translational applied research for the development and validation of novel properly functionalized luminescent conjugated polymers (LCP) that via modern imaging technology can give rise to entirely new and innovative methodology for studying neurodegenerative diseases. The objectives include the development of novel imaging agents that can be utilized for biomedical research, diagnosis, monitoring and prognosis, and for support and guidance of therapeutic interventions for Alzheimer’s disease and prion diseases. The consortium is composed of expert groups in experimental optics, polymer synthesis, magnetic resonance imaging (MRI), synthesis of functionalized magnetic nanoparticles, amyloid structure, AD mouse models, clinical AD, and prion diseases. At the same time this project establishes strategic links between mainly SME based Industries, expert researchers at universities and principal users in terms of hospitals. The project consortium will develop and share an efficient plan for dissemination and exploitation of the project results.
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Coordinator

LINKOPINGS UNIVERSITET

Address

Campus Valla
581 83 LinkÖPing

Sweden

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 1 294 852,80

Administrative Contact

Magnus Fredriksson (Dr.)

Participants (7)

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UNIVERSITE LYON 1 CLAUDE BERNARD

France

EU Contribution

€ 532 400

EBERHARD KARLS UNIVERSITAET TUEBINGEN

Germany

EU Contribution

€ 663 372

NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU

Norway

EU Contribution

€ 654 249

UNIVERSITAT ZURICH

Switzerland

EU Contribution

€ 558 867

CHARITE - UNIVERSITAETSMEDIZIN BERLIN

Germany

EU Contribution

€ 506 144

GENOVIS AB

Sweden

EU Contribution

€ 255 761,60

APPLIED SPECTRAL IMAGING LTD

Israel

EU Contribution

€ 512 448,40

Project information

Grant agreement ID: 242098

Status

Closed project

  • Start date

    1 November 2009

  • End date

    31 December 2012

Funded under:

FP7-HEALTH

  • Overall budget:

    € 6 475 643,20

  • EU contribution

    € 4 978 094,80

Coordinated by:

LINKOPINGS UNIVERSITET

Sweden