Objectif This ERC Grant proposal aims to explore the many challenges offered by non-covalent synthesis of functional supramolecular systems. This proposal will use the many possibilities of supramolecular polymers and how we envisage the construction of supramolecular compartmentalized systems based on specific secondary interactions. By studying the mechanisms of the formation of supramolecular polymers, new entrees are foreseen to limit the degree of supramolecular polymers by anti-cooperative mechanisms and to control both the depolymerization and polymerization aiming at supramolecular polymerization processes out of equilibrium. These insights will be used to design, synthesize and self-assembly materials that dynamically adapt their properties to cells that are brought in contact with these biomaterials. With these materials, parts of a bioartificial kidney will be made. With all the knowledge obtained through the years, we have recently introduced a concept to stepwise create folded macromolecules making use of our well-known supramolecular units. These single chain nanoparticles with internal structure are now proposed to be the starting point for making compartmentalized three-dimensional systems that possess functionality similar to proteins. Therefore, also novel techniques to synthesize well-defined polymers are introduced. Champ scientifique natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural scienceschemical sciencespolymer sciencesengineering and technologynanotechnologynano-materialsengineering and technologyindustrial biotechnologybiomaterials Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Thème(s) ERC-AG-PE5 - ERC Advanced Grant - Materials and Synthesis Appel à propositions ERC-2009-AdG Voir d’autres projets de cet appel Régime de financement ERC-AG - ERC Advanced Grant Institution d’accueil TECHNISCHE UNIVERSITEIT EINDHOVEN Contribution de l’UE € 1 947 937,00 Adresse GROENE LOPER 3 5612 AE Eindhoven Pays-Bas Voir sur la carte Région Zuid-Nederland Noord-Brabant Zuidoost-Noord-Brabant Type d’activité Higher or Secondary Education Establishments Contact administratif S. Sagitta Peters (Ms.) Chercheur principal Egbert Willem Meijer (Prof.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée Bénéficiaires (1) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire TECHNISCHE UNIVERSITEIT EINDHOVEN Pays-Bas Contribution de l’UE € 1 947 937,00 Adresse GROENE LOPER 3 5612 AE Eindhoven Voir sur la carte Région Zuid-Nederland Noord-Brabant Zuidoost-Noord-Brabant Type d’activité Higher or Secondary Education Establishments Contact administratif S. Sagitta Peters (Ms.) Chercheur principal Egbert Willem Meijer (Prof.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée