Obiettivo This ERC Grant proposal aims to explore the many challenges offered by non-covalent synthesis of functional supramolecular systems. This proposal will use the many possibilities of supramolecular polymers and how we envisage the construction of supramolecular compartmentalized systems based on specific secondary interactions. By studying the mechanisms of the formation of supramolecular polymers, new entrees are foreseen to limit the degree of supramolecular polymers by anti-cooperative mechanisms and to control both the depolymerization and polymerization aiming at supramolecular polymerization processes out of equilibrium. These insights will be used to design, synthesize and self-assembly materials that dynamically adapt their properties to cells that are brought in contact with these biomaterials. With these materials, parts of a bioartificial kidney will be made. With all the knowledge obtained through the years, we have recently introduced a concept to stepwise create folded macromolecules making use of our well-known supramolecular units. These single chain nanoparticles with internal structure are now proposed to be the starting point for making compartmentalized three-dimensional systems that possess functionality similar to proteins. Therefore, also novel techniques to synthesize well-defined polymers are introduced. Campo scientifico natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural scienceschemical sciencespolymer sciencesengineering and technologynanotechnologynano-materialsengineering and technologyindustrial biotechnologybiomaterials Programma(i) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Argomento(i) ERC-AG-PE5 - ERC Advanced Grant - Materials and Synthesis Invito a presentare proposte ERC-2009-AdG Vedi altri progetti per questo bando Meccanismo di finanziamento ERC-AG - ERC Advanced Grant Istituzione ospitante TECHNISCHE UNIVERSITEIT EINDHOVEN Contributo UE € 1 947 937,00 Indirizzo GROENE LOPER 3 5612 AE Eindhoven Paesi Bassi Mostra sulla mappa Regione Zuid-Nederland Noord-Brabant Zuidoost-Noord-Brabant Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo S. Sagitta Peters (Ms.) Ricercatore principale Egbert Willem Meijer (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Beneficiari (1) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto TECHNISCHE UNIVERSITEIT EINDHOVEN Paesi Bassi Contributo UE € 1 947 937,00 Indirizzo GROENE LOPER 3 5612 AE Eindhoven Mostra sulla mappa Regione Zuid-Nederland Noord-Brabant Zuidoost-Noord-Brabant Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo S. Sagitta Peters (Ms.) Ricercatore principale Egbert Willem Meijer (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato
