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The Integrated Neurobiology of Food Intake, Addiction and Stress

The Integrated Neurobiology of Food Intake, Addiction and Stress

Objective

NeuroFAST is a multidisciplinary project, involving ten teams from seven countries, to explore the neurobiology of addiction and eating behaviour and the complex socio-psychological forces that can lead to its dysregulation. These forces include dietary components (including highly palatable foods and alcohol), some of which may have addictive properties, but also cultural and social pressures, everyday stressors, and family-genetic influences on these. The project will provide new data from human studies, including human nutritional studies, that is needed to inform health policy initiatives. This will be underpinned by state-of-the art mechanistic research to establish a solid scientific basis for this advice. The European added value lies in building up the necessary critical mass in several fields of expertise: psychology, epidemiology, human genetics related to eating disorders, human nutrition, eating and addictive behaviour disorders, endocrinology, human brain imaging, together with studies of the basic mechanisms of eating behaviour and addiction, (neuro)endocrine regulators, stress, opiate dependence, and cannabinoid actions. To provide scientific support for European public health policies, a focus will be on a socio-psychological analysis of determinants of food addiction and substance abuse, and of how risk factors like stress in the workplace are driving addictive behaviour. We will establish an evidence base for inter-relationships, linking eating disorder research with obesity research, stress research and addiction research, and involving studies of selected individual food components using novel designed foods with controlled components. In summary, we will use a synergistic combination of controlled laboratory studies, characterization of patient groups, and examination of real-world scenarios based on epidemiological community samples that will be relevant to policy development.
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Coordinator

GOETEBORGS UNIVERSITET

Address

Vasaparken
405 30 Goeteborg

Sweden

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 1 606 120

Administrative Contact

Emilia Rung (Dr.)

Participants (12)

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Utrecht University Medical Center

Netherlands

EU Contribution

€ 591 800

ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA

Italy

EU Contribution

€ 217 790

THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN

United Kingdom

EU Contribution

€ 924 079

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE

United Kingdom

EU Contribution

€ 245 800

UNIVERSITAETSKLINIKUM ESSEN

Germany

EU Contribution

€ 507 470

THE UNIVERSITY OF EDINBURGH

United Kingdom

EU Contribution

€ 662 345

TECHNISCHE UNIVERSITAET DRESDEN

Germany

EU Contribution

€ 159 100

UNIVERSIDAD DE SANTIAGO DE COMPOSTELA

Spain

EU Contribution

€ 207 780

INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES

Hungary

EU Contribution

€ 227 800

NIZO FOOD RESEARCH BV

Netherlands

EU Contribution

€ 292 100

CONSIGLIO NAZIONALE DELLE RICERCHE

Italy

EU Contribution

€ 307 800

FONDAZIONE TOSCANA GABRIELE MONASTERIO PER LA RICERCA MEDICA E DI SANITA PUBBLICA

Italy

EU Contribution

€ 50 000

Project information

Grant agreement ID: 245009

Status

Closed project

  • Start date

    1 April 2010

  • End date

    31 March 2015

Funded under:

FP7-KBBE

  • Overall budget:

    € 7 976 148,20

  • EU contribution

    € 5 999 984

Coordinated by:

GOETEBORGS UNIVERSITET

Sweden