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Multi-disciplinary biodosimetric tools to manage high scale radiological casualties

Objective

In the event of a large scale radiological emergency biological dosimetry is an essential tool that can provide timely assessment of radiation exposure to the general population and enable the identification of those exposed people, who should receive medical treatment. A number of biodosimetric tools are potentially available, but they must be adapted and tested for a large-scale emergency scenario. These methods differ in their specificity and sensitivity to radiation, the stability of signal and speed of performance. A large scale radiological emergency can take different forms. Based on the emergency scenario different biodosimetric tools should be applied so that the dosimetric information can be made available with optimal speed and precision. The aim of this multi-disciplinary collaborative project is to analyse a variety of biodosimetric tools and adapt them to different mass casualty scenarios. The following biodosimetric tools will be validated and established: the dicentric assay, the micronucleus assay, the gamma-H2AX assay, the skin speckle assay, the blood serum protein expression assay and EPR/OSL dosimetry in components of pocket electronic devises. The assays were chosen because they complement each other with respect to sensitivity, specificity to radiation and the exposure scenario as well as speed of performance. The project will involve the key European players with extensive experience in biological dosimetry. Training will be carried out and automation and commercialisation pursued. An operational guide will be developed and disseminated among emergency preparedness and radiation protection organisations. The final deliverable of this project will be establishment of a biodosimetric network that is fully functional and ready to respond in case of a mass casualty. Thus, the project will strengthen the European security capabilities by achieving tangible results.
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Coordinator

STOCKHOLMS UNIVERSITET

Address

Universitetsvagen 10
10691 Stockholm

Sweden

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 536 149,40

Participants (15)

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BUNDESAMT FUER STRAHLENSCHUTZ

Germany

EU Contribution

€ 228 000

UNIVERSITEIT GENT

Belgium

EU Contribution

€ 288 960

Public Health England an Executive Agency of the Dept of Health

United Kingdom

EU Contribution

€ 336 575,25

INSTITUT DE RADIOPROTECTION ET DE SURETE NUCLEAIRE

France

EU Contribution

€ 780 732,50

ISTITUTO SUPERIORE DI SANITA

Italy

EU Contribution

€ 199 800

DIREKTORATET FOR STRALEVERN OG ATOMSIKKERHET

Norway

EU Contribution

€ 122 325

SATEILYTURVAKESKUS

Finland

EU Contribution

€ 174 652,50

UNIVERSITAT AUTONOMA DE BARCELONA

Spain

EU Contribution

€ 86 400

INSTYTUT CHEMII I TECHNIKI JADROWEJ

Poland

EU Contribution

€ 85 140

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH

Germany

EU Contribution

€ 166 637,70

UNIVERSITAET ULM

Germany

EU Contribution

€ 228 960

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD

United Kingdom

EU Contribution

€ 100 680

EUROPEAN RADIATION DOSIMETRY GROUP

Germany

EU Contribution

€ 12 600

WESTLAKES SCIENTIFIC CONSULTING LTD

United Kingdom

Department of Health

United Kingdom

EU Contribution

€ 145 587,25

Project information

Grant agreement ID: 241536

Status

Closed project

  • Start date

    1 May 2010

  • End date

    30 April 2013

Funded under:

FP7-SECURITY

  • Overall budget:

    € 4 580 243,01

  • EU contribution

    € 3 493 199,60

Coordinated by:

STOCKHOLMS UNIVERSITET

Sweden

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