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Aggregate and Cumulative Risk Of Pesticides: an On-Line Integrated Strategy

Objective

EU Directive 396/2005 states that methods are needed to account for cumulative and aggregate exposure in pesticides regulation . 27% of food samples had multiple residues in the 2006 EU residue monitoring report. The Eurobarometer shows pesticides are one of the principal worries of EU consumers regarding food safety. Industry needs clear criteria to decide on large investments in product development. The central aim of the ACROPLIS project is: to develop a framework for cumulative and aggregate risk assessment of pesticides in an understandable way, accessible for all actors involved in European risk assessment and management. ACROPOLIS will: 1) study the data needs, data availability and uncertainties for cumulative exposure and effect assessment in a probabilistic risk assessment framework; 2) integrate models describing various routes of exposure into an aggregate exposure model; 3) develop new toxicological approaches for identifying possible additive or synergistic effects and developing a strategy for refinement of cumulative assessment groups; 4) integrate cumulative and aggregate risk models including uncertainty analyses in a web-based tool, including accessible data for all stakeholders; 5) improve risk assessment strategies in Europe by analysing stakeholders attitudes, by training and by discussing the new methodology in several stakeholder conferences. The project brings together the key experts and models in Europe including dietary exposure MCRA, dermal and inhalation exposure ConsExpo, user exposure EUROPOEM and UK POEM, dose-response PROAST and risk characterisation IPRA. The new integrated model will be tested in case studies with conazoles and pyrethroids and validated with biomarker and duplicate diet studies. The model software will be tested in different countries to ensure its usability at the international level. Overall ACROPOLIS will advance the scientific foundation to meet policy needs, protect EU consumers and address their concerns.

Field of science

  • /natural sciences/computer and information sciences/software
  • /engineering and technology/other engineering and technologies/food and beverages/food safety

Call for proposal

FP7-KBBE-2009-3
See other projects for this call

Funding Scheme

CP-FP - Small or medium-scale focused research project

Coordinator

RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU
Address
Antonie Van Leeuwenhoeklaan 9
3721 MA Bilthoven
Netherlands
Activity type
Research Organisations
EU contribution
€ 761 450,26
Administrative Contact
Jacob Van Klaveren (Mr.)

Participants (11)

ISTITUTO NAZIONALE DI RICERCA PER GLI ALIMENTI E LA NUTRIZIONE

Participation ended

Italy
Address
Via Ardeatina, 546
00178 Roma
Activity type
Research Organisations
Administrative Contact
Aida Turrini (Dr.)
Food and Environment Research Agency
United Kingdom
EU contribution
€ 559 916,76
Address
Area 1A, Nobel House, Smith Square 17
SW1P 3JR London
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Richard Glass (Dr.)
UNIVERSITA DEGLI STUDI DI MILANO
Italy
EU contribution
€ 453 088,20
Address
Via Festa Del Perdono 7
20122 Milano
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Monica Gritti (Dr.)
CONSIGLIO PER LA RICERCA IN AGRICOLTURA E L'ANALISI DELL'ECONOMIA AGRARIA
Italy
EU contribution
€ 116 370
Address
Via Po 14
00198 Roma
Activity type
Research Organisations
Administrative Contact
Aida Turrini (Dr.)
UNIVERSITEIT UTRECHT
Netherlands
EU contribution
€ 346 251,50
Address
Heidelberglaan 8
3584 CS Utrecht
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Remco Westerink (Dr.)
HEALTH AND SAFETY EXECUTIVE
United Kingdom
EU contribution
€ 95 638,50
Address
Merton Road, Redgrave Court
L20 7HS Bootle Merseyside
Activity type
Research Organisations
Administrative Contact
Paul Y. Hamey (Mr.)
STATNI ZDRAVOTNI USTAV
Czechia
EU contribution
€ 50 906,40
Address
Srobarova 48
10042 Praha 10
Activity type
Research Organisations
Administrative Contact
Jiri Ruprich (Dr.)
EUROPEAN FRESH PRODUCE ASSOCIATION AISBL
Belgium
EU contribution
€ 40 334,40
Address
Rue De Treves 49-51
1040 Bruxelles
Activity type
Other
Administrative Contact
Philippe Binard (Mr.)
LIVSMEDELS VERKET
Sweden
EU contribution
€ 102 375
Address
Hamnesplanaden 5
751 26 Uppsala
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Salomon Sand (Dr.)
UNIVERSITEIT GENT
Belgium
EU contribution
€ 96 480
Address
Sint Pietersnieuwstraat 25
9000 Gent
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Nathalie Van De Pitte (Ms.)
STICHTING WAGENINGEN RESEARCH
Netherlands
EU contribution
€ 372 736,98
Address
Droevendaalsesteeg 4
6708 PB Wageningen
Activity type
Research Organisations
Administrative Contact
A. Jansen