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Three modality contrast imaging using multi-functionalized microballoons

Objective

In vivo multimodality imaging is a fast growing field in medical research and, although the achievements at clinical level of this diagnostic method are recent, it is already one of the most promising approaches in the diagnosis of diseases in many research addressed medical centres. At present in this area, the USA plays the protagonist role as a result of the amount of resources engaged in the arena in the last decade. Both government and private companies agree, when considering the potential of this approach, that it is one of the foremost medical advancements as it will lead to early diagnosis of diseases with high impact on the societies of western countries. Multimodality imaging is currently viewed as a simple and powerful integration of two or more imaging methods (e.g. PET-CT). 3MICRON is an ambitious project which gathers some of the most advanced European medical and technical institutions together to address the design of new strategies in diagnostics, and to push the potential of medical imaging beyond the state-of-the-art. The multimodality approaches are supported by a class of next-generation micro/nanodevices called microballoons. These subsystems are able to implement the function of an ultrasound contrast agent with other imaging methods (SPECT, MRI). In the future, they may act as a minimally invasive drug delivery method and hyperthermia device. In 3MICRON, this multi-functional device will be tested in vitro and in vivo in order to assess bioclearance and cytoxicity effects toward high impact diseases, e.g. cardiovascular and inflammation pathologies. Finally, selected types of microballoons will undergo pre-clinical screening for a consolidated assessment of the “bench-to-bed” pathway for these new microdevices.

Field of science

  • /medical and health sciences/clinical medicine/radiology/medical imaging

Call for proposal

FP7-NMP-2009-LARGE-3
See other projects for this call

Funding Scheme

CP-IP - Large-scale integrating project

Coordinator

KUNGLIGA TEKNISKA HOEGSKOLAN
Address
Brinellvagen 8
100 44 Stockholm
Sweden
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 114 342
Administrative Contact
Peta Sjölander (Dr.)

Participants (9)

UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA
Italy
EU contribution
€ 449 263
Address
Via Cracovia 50
00133 Roma
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Maria Letizia Terranova (Prof.)
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Ireland
EU contribution
€ 488 942
Address
Belfield
4 Dublin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Gillian Boyle (Ms.)
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 1 072 752
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Tommy Spångö (Mr.)
FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI
Italy
EU contribution
€ 154 154
Address
Via Venezian 1
20133 Milan
Activity type
Research Organisations
Administrative Contact
Antonio Cannarozzo (Dr.)
Surflay Nanotec GmbH
Germany
EU contribution
€ 571 626
Address
Max Planck Strasse 3
12489 Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Lars Dähne (Dr.)
UNIVERSITAT BAYREUTH
Germany
EU contribution
€ 626 610
Address
Universitatsstrasse 30
95447 Bayreuth
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Marcus Urban (Mr.)
ESAOTE SPA
Italy
EU contribution
€ 468 026
Address
Viale Bianca Maria 25
20122 Milano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Sergio Paddeu (Dr.)
STIFTELSEN SINTEF
Norway
EU contribution
€ 468 291
Address
Strindveien 4
7034 Trondheim
Activity type
Research Organisations
Administrative Contact
Solfrid Sørensen (Ms.)
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany
EU contribution
€ 585 406
Address
Im Neuenheimer Feld 280
69120 Heidelberg
Activity type
Research Organisations
Administrative Contact
Bettina Crispin