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NANOTECHNOLOGICAL TOOLKITS FOR MULTI-MODAL DISEASE DIAGNOSTICS AND TREATMENT MONITORING

Objective

NAMDIATREAM will develop a cutting edge nanotechnology-based toolkit for multi-modal detection of biomarkers of most common cancer types and cancer metastases, permitting identification of cells indicative of early disease onset in a high-specificity and throughput format in clinical, laboratory and point-of-care devices. The project is built on the innovative concepts of super-sensitive and highly specific “lab-on-a-bead”, “lab-on-a-chip” and “lab-on-a-wire” nano-devices utilizing photoluminescent, plasmonic, magnetic and non-linear optical properties of nanomaterials. This offers groundbreaking advantages over present technologies in terms of stability, sensitivity, time of analysis, probe multiplexing, assay miniaturisation and reproducibility. The ETP in Nanomedicine documents point out that nanotechnology has yet to deliver practical solutions for the patients and clinicians in their struggle against common, socially and economically important diseases such as cancer. Over 3.2M new cases and 1.7M cancer-related deaths are registered in Europe every year, largely because diagnostic methods have an insufficient level of sensitivity, limiting their potential for early disease identification. We will deliver •Photoluminescent nanoparticle-based reagents and diagnostic chips for high throughput early diagnosis of cancer and treatment efficiency assessment •Nanocrystals enabling plasmon-optical and nonlinear optical monitoring of molecular receptors within body fluids or on the surface of cancer cell •Multi-Parameter screening of cancer biomarkers in diagnostic material implementing segmented magnetic nanowires •Validation of nano-tools for early diagnosis and highly improved specificity in cancer research. •OECD-compliant nanomaterials with improved stability, signal strength and biocompatibility Direct lead users of the results will be the diagnostic and medical imaging device companies involved in the consortium, clinical and academic partners

Field of science

  • /engineering and technology/nanotechnology/nano-materials/nanocrystal
  • /engineering and technology/nanotechnology
  • /medical and health sciences/medical biotechnology/nanomedicine
  • /medical and health sciences/clinical medicine/oncology/cancer
  • /medical and health sciences/clinical medicine/radiology/medical imaging
  • /engineering and technology/nanotechnology/nano-materials

Call for proposal

FP7-NMP-2009-LARGE-3
See other projects for this call

Funding Scheme

CP-IP - Large-scale integrating project

Coordinator

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Address
College Green
2 Dublin
Ireland
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 2 438 665,90
Administrative Contact
Deirdre Savage (Ms.)

Participants (22)

Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE

Participation ended

Spain
EU contribution
€ 69 667
Address
Tolosa Hiribidea 76
20018 San Sebastian
Activity type
Research Organisations
Administrative Contact
Miguel Odriozola (Mr.)
AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH
Austria
EU contribution
€ 692 912
Address
Giefinggasse 4
1210 Wien
Activity type
Research Organisations
Administrative Contact
Felix Schropfer (Mr.)
UNIVERSITE DE GENEVE
Switzerland
EU contribution
€ 728 240
Address
Rue Du General Dufour 24
1211 Geneve
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Pierre Spierer (Prof.)
PHILIPPS UNIVERSITAET MARBURG
Germany
EU contribution
€ 444 400
Address
Biegenstrasse 10
35037 Marburg
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Wolfgang Parak (Prof.)
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Ireland
EU contribution
€ 496 102
Address
Belfield
4 Dublin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Donal Doolan (Mr.)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
EU contribution
€ 463 470
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
Administrative Contact
Dominique Nobile (Mr.)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE
France
EU contribution
€ 466 583
Address
Avenue De Rangueil 135
31077 Toulouse
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Didier Marquis (Prof.)
TECHNISCHE UNIVERSITAET BRAUNSCHWEIG
Germany
EU contribution
€ 464 140
Address
Universitaetsplatz 2
38106 Braunschweig
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Meinhard Schilling (Prof.)
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Switzerland
EU contribution
€ 597 633
Address
Batiment Ce 3316 Station 1
1015 Lausanne
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Paul Joseph Dyson (Prof.)
UNIVERSITE SAVOIE MONT BLANC
France
EU contribution
€ 278 912
Address
Rue Marcoz 27 Domaine Universitaire
73011 Chambery
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Philippe Carron (Dr.)
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany
EU contribution
€ 448 500
Address
Hofgartenstrasse 8
80539 Munich
Activity type
Other
Administrative Contact
Nils Brose (Prof.)
Becton Dickinson France SAS
France
EU contribution
€ 499 200
Address
Rue Aristide - Berges 11
38800 Le Pont De Claix
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Emiel Jans (Mr.)
NIKON FRANCE SAS
France
EU contribution
€ 319 435,60
Address
Rue Du Marche Rollay 191
94504 Champigny Sur Marne Cedex
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Valerie Le Lay (Ms.)
PROGENIKA BIOPHARMA SA
Spain
EU contribution
€ 667 280
Address
Parque Ibaizabal Bidea Edificio 504 Parque Tecnologico Derio
48160 Vizcaya Bizkaia
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Maria Martinez (Ms.)
INNOVA SRL
Italy
EU contribution
€ 435 257,50
Address
Via Cicerone, 66
00193 Roma
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Francesca Stinelli (Ms.)
CELLIX LIMITED
Ireland
EU contribution
€ 435 020
Address
Long Mile Road Unit 1
12 Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Vivienne Williams (Ms.)
Selective Antibodies Limited
United Kingdom
EU contribution
€ 677 080
Address
Cels At Newcastle William Leech Building Framlington Place
NE2 4HH Newcastle Upon Tyne
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Colin Self (Prof.)
NANOSIGHT LIMITED
United Kingdom
EU contribution
€ 97 950
Address
London Road Minton Park
SP4 7RT Wiltshire
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Jeremy Warren (Mr.)
RADISENS DIAGNOSTICS LIMITED
Ireland
EU contribution
€ 465 650
Address
Units 1-3 Westpoint Buildings Link Road Ballincoll
IP31 HF29 Cork
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Jerry O'brien (Mr.)
Advanced Accelerator Applications
France
EU contribution
€ 333 954
Address
Rue Diesel 20
01630 Saint Genis Pouilly
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Heinz Mausli (Dr.)
FORSCHUNGSINSTITUT FUR MINERALISCHEUND METALLISCHE WERKSTOFFE EDELSTEINE/EDELMETALLE GMBH
Germany
EU contribution
€ 274 913
Address
Struthstrasse 2
55716 Idar Oberstein
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Daniel Rytz (Dr.)
UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE
France
EU contribution
€ 204 240
Address
Boulevard De La Paix 9 Villa Douce
51100 Reims
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Nathalie Rau (Mrs.)