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Advanced interfaced microsystems Research for analysis of Real-wOrld clinical, food, environmental and Waste Samples

Advanced interfaced microsystems Research for analysis of Real-wOrld clinical, food, environmental and Waste Samples

Objective

The goal of ARROWS is to develop a microengineered platform for the analysis of 'real-world' samples from the food, drink and healthcare industries. The principle deliverable will be a chip-scale capillary electrophoresis/liquid chromatography mass spectrometer (CE/LC-MS) that matches the performance of today's mainframe systems.
The ARROWS innovation is to integrate and interface multiple chip technologies into a platform capable of analysing messy, sticky biological matrices like tissue, food, blood and urine. Our vision is to offer users from the food, environmental and clinical sectors 'more for less' by delivering the functionality of a laboratory-scale, high-end CE/LC-MS system, which today is the size of a filing cabinet, in a mass-deployable tool the size of a desktop PC.
Next-generation micro-analytical devices from Tyndall, Microsaic, VTT and CSEM will be combined into powerful, multi-sensing tools capable of identifying trace quantities of the chemical species of interest (e.g. pesticides, disease biomarkers) in complex biological matrices such as tissue, food and drinking water. Microsaic Systems will develop a MS based on patented ionchip technology.
CE/LC/MS is a universal technique and analytical applications are unlimited. Initially, ARROWS will focus on two applications: (a) detection of cancer biomarkers in fractional spots found on tissue, and (b) screening of imported food for contamination. End-users Charité Universitätsmedizin Berlin and DEFRA will evaluate the platform.
ARROWS utilizes the consortium's 'best-in-class' capabilities to exploit the scaling laws associated with microfluidics, chip-based chromatography and electrophoresis and microengineered advanced mass spectrometry to minimise analysis time, sample volume and reduce manufacturing costs. These scaling laws address the cross-cutting issue of sustainability by reducing solvent consumption, waste and power consumption by orders of magnitude.
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Coordinator

UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK

Address

Western Road
T12 Yn60 Cork

Ireland

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 910 113

Administrative Contact

Conor Delaney (Mr.)

Participants (5)

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CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT

Switzerland

EU Contribution

€ 479 767

CHARITE - UNIVERSITAETSMEDIZIN BERLIN

Germany

EU Contribution

€ 173 778

TEKNOLOGIAN TUTKIMUSKESKUS VTT

Finland

EU Contribution

€ 666 863

THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS

United Kingdom

EU Contribution

€ 100 978

MICROSAIC SYSTEMS

United Kingdom

EU Contribution

€ 964 774

Project information

Grant agreement ID: 257669

Status

Closed project

  • Start date

    1 July 2010

  • End date

    31 December 2013

Funded under:

FP7-ICT

  • Overall budget:

    € 4 335 640

  • EU contribution

    € 3 296 273

Coordinated by:

UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK

Ireland