Targeting nucleic acid structures by site-directed ligand discovery

Projektinformationen

TNSBSLD

ID Finanzhilfevereinbarung: 253562

Abgeschlossenes Projekt

Startdatum 1 Mai 2010

Enddatum 30 April 2012

Finanziert unter

• Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Gesamtkosten € 172 240,80

EU-Beitrag € 172 240,80

Koordiniert durch

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom

Ziel

Nucleic acids and nucleic acid-protein interactions play an important role in biological processes of medical importance and can be considered as attractive targets for drug design. Small molecules or peptides that interact with such targets and control their functions are of great interest. Thus there is a need for a general method for rapidly identifying such low molecular weight small molecules or peptides. The focus of this proposal is to establish a new method based on a combined fragment-based and site-directed approach that exploits the power of dynamic combinatorial chemistry (DCC). This method will be used as a general strategy to target functional nucleic acid structures and their protein complexes.

Wissenschaftliches Gebiet

• natural sciences › biological sciences › biochemistry › biomolecules › nucleic acids
• medical and health sciences › basic medicine › medicinal chemistry
• natural sciences › biological sciences › biochemistry › biomolecules › proteins

Programm/Programme

• FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Thema/Themen

• FP7-PEOPLE-2009-IEF - Marie Curie Action: "Intra-European Fellowships for Career Development"

Aufforderung zur Vorschlagseinreichung

FP7-PEOPLE-2009-IEF
Andere Projekte für diesen Aufruf anzeigen

Finanzierungsplan

MC-IEF - Intra-European Fellowships (IEF)

Koordinator

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE

Kontakt Verwaltung

Keith Cann (Mr.)

• EU-Beitrag: € 172 240,80
• Adresse: TRINITY LANE THE OLD SCHOOLS ; CB2 1TN Cambridge ; Vereinigtes Königreich
• Region: East of England › East Anglia › Cambridgeshire CC
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: Keine Daten