Descrizione del progetto Microsystems and Smart Miniaturised Systems Mostra l’obiettivo del progetto Nascondi l’obiettivo del progetto By integrating and interfacing multiple core technologies and related materials from fluidics and photonics technology to porous silicon (porSi) and polymers, Positive will target the implementation of a microsystem tailored to a specific application with a key societal and economic need. The very high surface to volume ratio of porSi permits very high surface densities of bound antibody-antigen complexes in a reduced volume that through a novel optical interaction leads to scores of sensing areas on a 1cm2 chip with detection-limits down to ~0.1 pg/mm2, significantly beyond state of the art for highly integrated label free sensors at point of care. This offers the further advantageous possibility of assaying several parameters simultaneously (multi-assay) leading to further increases in the reliability and reductions in the measurement uncertainty of a diagnostic over single-parameter assays. The novel Lab-on-Chip technology has the potential to be fast and easy to use, making routine screening or monitoring with immunoassays more cost-effective.The ultimate goal of Positive will be to demonstrate a safe and rapid low cost diagnostic test for food allergies at point of care such as in a GP's office or hospital. A quantitative determination of allergy sensitization is expected within ~15' of adding no more than 100µl of blood. A final prototype consisting of a packaged biochip and reader will be used on clinical samples in order to determine sensitization to allergens such as that for hen's eggs, cow's milk, peanuts, wheat, treenuts, fish, sesame, and shrimp ingestion.The two industrial partners with their international market strategies and a clinical specialist for food allergies in children as an end-user will enable us to target the whole value chain from research to validation. It is therefore expected that this novel and beyond state of the art Lab-on -Chip will give impetus to the global competitiveness and profitability of European industry in Microsystems activities.During the course of the project, after several different lengthy and comprehensive exploratory activities, it was realised that the development of a suitable porous silicon membrane for a marketable Positive biosensor platform, if possible could not be done within the lifetime of the project. In parallel, porous alumina was found to have both optimal fluidic and similar optical properties as well as being commericially available at a low cost and with less or no problems for freedom to operate as part of a final commericial Positive platform. For that reason, some porSi related objectives, milestones, deliverables and tasks have been cancelled. Campo scientifico engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsbiosensorsmedical and health sciencesclinical medicineallergologyfood allergyengineering and technologyother engineering and technologiesmicrotechnologylab on a chipnatural scienceschemical sciencespolymer sciencesnatural scienceschemical sciencesinorganic chemistrymetalloids Programma(i) FP7-ICT - Specific Programme "Cooperation": Information and communication technologies Argomento(i) ICT-2009.3.9 - Microsystems and smart miniaturised systems Invito a presentare proposte FP7-ICT-2009-5 Vedi altri progetti per questo bando Meccanismo di finanziamento CP - Collaborative project (generic) Coordinatore UNIVERSITAT DE VALENCIA Contributo UE € 427 158,00 Indirizzo AVENIDA BLASCO IBANEZ 13 46010 Valencia Spagna Mostra sulla mappa Regione Este Comunitat Valenciana Valencia/València Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Angeles Sanchis (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (7) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT Svizzera Contributo UE € 700 439,00 Indirizzo RUE JAQUET DROZ 1 2000 Neuchatel Mostra sulla mappa Regione Schweiz/Suisse/Svizzera Espace Mittelland Neuchâtel Tipo di attività Research Organisations Contatto amministrativo Helmut Knapp (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato CHARITE - UNIVERSITAETSMEDIZIN BERLIN Germania Contributo UE € 255 158,00 Indirizzo Chariteplatz 1 10117 Berlin Mostra sulla mappa Regione Berlin Berlin Berlin Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Eveline Fräßdorf (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato PHYLOGENE Francia Contributo UE € 159 973,00 Indirizzo 62RTE Nationale 113 30620 Bernis Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo gilbert Skorski (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato CONSIGLIO NAZIONALE DELLE RICERCHE Italia Contributo UE € 311 015,00 Indirizzo PIAZZALE ALDO MORO 7 00185 Roma Mostra sulla mappa Regione Centro (IT) Lazio Roma Tipo di attività Research Organisations Contatto amministrativo Riva Sergio (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIVERSITA DEGLI STUDI DI TRENTO Italia Contributo UE € 323 072,00 Indirizzo VIA CALEPINA 14 38122 Trento Mostra sulla mappa Regione Nord-Est Provincia Autonoma di Trento Trento Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Lorenzo Pavesi (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato KUNGLIGA TEKNISKA HOEGSKOLAN Svezia Contributo UE € 335 617,00 Indirizzo BRINELLVAGEN 8 100 44 Stockholm Mostra sulla mappa Regione Östra Sverige Stockholm Stockholms län Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Erika Appel (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Farfield Group Limited Regno Unito Contributo UE € 387 568,00 Indirizzo Farfield House, Southmere Court, Electra Way, Crewe Business Park CWI 6GU Crewe Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Louise Madden (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato