Cel For the first time the possibility to change certain species sex while maintaining their original sex chromosomes is presented as an excellent opportunity to unravel aspects of sex chromosome evolution. Theory of sex chromosome evolution states that sexually antagonistic genes, i.e. genes that are beneficial to one sex but at the same time harmful to the opposite sex, should often be linked to one of the sex chromosomes. Current knowledge of which genes are responsible for such sexual antagonisms is however limited. The mosquitofish Gambusia affinis can easily be sex reversed and will represent the first ZW sex chromosome system besides birds where questions of sex-biased gene expression, dosage compensation and sex-biased expression through development will be addressed. Candidate sexual antagonistic genes will then be used to gain insight into expression differences in sex reversed individuals, such as male/female or sex-linked/autosomal dissimilarities in responsiveness to the new sex. Mainly, these objectives will be studied applying the new cutting-edge next-generation sequencing techniques (e.g. Roche 454, Illumina’s Solexa, etc.). This project has great potential to contribute both to the fellows and to the European excellence. Through careful planning of training in research and auxiliary topics it is aimed at providing the fellow with complementary skills needed to commence a career as an independent leading scientist. Dziedzina nauki natural sciencesbiological sciencesgeneticschromosomes Program(-y) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Temat(-y) FP7-PEOPLE-2009-IEF - Marie Curie Action: "Intra-European Fellowships for Career Development" Zaproszenie do składania wniosków FP7-PEOPLE-2009-IEF Zobacz inne projekty w ramach tego zaproszenia System finansowania MC-IEF - Intra-European Fellowships (IEF) Koordynator UPPSALA UNIVERSITET Wkład UE € 171 328,60 Adres VON KRAEMERS ALLE 4 751 05 Uppsala Szwecja Zobacz na mapie Region Östra Sverige Östra Mellansverige Uppsala län Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Karin Olsson (Ms.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych