Objective Plant growth is remarkably flexible in response to changing environmental conditions, which is especially important as human life depends on the production of plant materials and they are now also being explored as a source of non-fossil fuels. The proposed project aims to reveal novel regulatory mechanisms that control developmental processes in response to environmental stresses. Mitogen-activated protein (MAP) kinase pathways have been in the focus of stress signalling research in plants for over a decade. On the other hand our recent results strongly suggest a role for a MAP kinase pathway in the regulation of meristem activity. We propose that the underlying mechanism is the regulation of transcription factors that are key regulators of stem cell identity and meristem development by direct MAP kinase phosphorylation. This notion is supported by our bioinformatics prediction of potential MAP kinase substrates as well as by proteomics data. Our goal is to generate biochemical and functional genetics evidence for the cross-talk between known MAP kinase and meristem regulatory pathways in the model plant Arabidopsis. To this end we will commence with testing the phosphorylation status of candidate MAP kinase substrates using efficient novel approaches. In the second part of the project a couple of the most intriguing substrates and their relation to MAP kinase pathways will be genetically analysed. Thus the proposed experimental program can provide important novel biological information of major agricultural significance. Fields of science natural sciencesbiological sciencesgeneticsnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsproteomicsmedical and health sciencesmedical biotechnologycells technologiesstem cellsengineering and technologyenvironmental engineeringenergy and fuels Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) FP7-PEOPLE-2009-RG - Marie Curie Action: "Reintegration Grants" Call for proposal FP7-PEOPLE-2009-RG See other projects for this call Funding Scheme MC-ERG - European Re-integration Grants (ERG) Coordinator AGRARTUDOMANYI KUTATOKOZPONT EU contribution € 45 000,00 Address BRUNSZVIK STREET 2 2462 Martonvasar Hungary See on map Region Dunántúl Közép-Dunántúl Fejér Activity type Research Organisations Administrative Contact Zoltán Bedő (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all Agricultural Research Institute of the Hungarian Academy of Sciences Participation ended Hungary EU contribution No data Address Brunszvik 2 2462 Martonvásár See on map Activity type Research Organisations Administrative Contact Zoltán Bedő (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data
