Role of the Cullin7 E3 ubiquitin ligase in insulin signaling and diabetes

Projektinformationen

CUL7 AND DIABETES

ID Finanzhilfevereinbarung: 256584

Abgeschlossenes Projekt

Startdatum 1 Januar 2011

Enddatum 31 Dezember 2014

Finanziert unter

• Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Gesamtkosten € 100 000,00

EU-Beitrag € 100 000,00

Koordiniert durch

TECHNISCHE UNIVERSITAET MUENCHEN
Germany

Ziel

This grant application is formulated to explore the biological role of the Cullin7 (CUL7) E3 ubiquitin ligase in insulin signaling and its implication for diabetes. My previous work led to the identification of insulin receptor substrate 1 (IRS-1) as the proteolytic target of the CUL7 E3 ligase and uncovered CUL7 as a novel regulator of insulin signaling. Based on these observations, I will employ experimental strategies as outlined in this proposal to delineate CUL7`s role for the cellular insulin response and its contribution to insulin resistance and type 2 diabetes.

Wissenschaftliches Gebiet

• medical and health sciences › clinical medicine › endocrinology › diabetes

Programm/Programme

• FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Thema/Themen

• FP7-PEOPLE-2009-RG - Marie Curie Action: "Reintegration Grants"

Aufforderung zur Vorschlagseinreichung

FP7-PEOPLE-2009-RG
Andere Projekte für diesen Aufruf anzeigen

Finanzierungsplan

MC-IRG - International Re-integration Grants (IRG)

Koordinator

TECHNISCHE UNIVERSITAET MUENCHEN

Kontakt Verwaltung

Ulrike Ronchetti (Ms.)

• EU-Beitrag: € 100 000,00
• Adresse: Arcisstrasse 21 ; 80333 Muenchen ; Deutschland
• Region: Bayern › Oberbayern › München, Kreisfreie Stadt
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: Keine Daten